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β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling.
Mathew J, Zhou B, Haney RS, Kunz KA, Do Amaral LS, Roy Chowdhury R, Butler JH, Li H, Chakraborty AJ, Tabassum A, Bremers EK, Merino EF, Coyle R, Lee MCS, Baud D, Brand S, Totrov M, Cassera MB, Carlier PR. Mathew J, et al. Among authors: kunz ka. ACS Infect Dis. 2024 Nov 8;10(11):3951-3962. doi: 10.1021/acsinfecdis.4c00653. Epub 2024 Oct 28. ACS Infect Dis. 2024. PMID: 39466084
Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials.
Mathew J, Ding S, Kunz KA, Stacy EE, Butler JH, Haney RS, Merino EF, Butschek GJ, Rizopoulos Z, Totrov M, Cassera MB, Carlier PR. Mathew J, et al. Among authors: kunz ka. ACS Med Chem Lett. 2022 Feb 23;13(3):365-370. doi: 10.1021/acsmedchemlett.1c00663. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35300096 Free PMC article.
Synthesis of N2-Substituted 1,2,3-Triazoles.
Kunz KA, Springer BL, Klahn P, Aldemir H, Mohr F, Kirsch SF. Kunz KA, et al. Org Lett. 2024 Oct 18;26(41):8816-8820. doi: 10.1021/acs.orglett.4c03204. Epub 2024 Oct 8. Org Lett. 2024. PMID: 39378272