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Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2.
Vecchiarelli HA, Bisht K, Sharma K, Weiser Novak S, Traetta ME, Garcia-Segura ME, St-Pierre MK, Savage JC, Willis C, Picard K, Bordeleau M, Vernoux N, Khakpour M, Garg R, Loewen SM, Murray CJ, Grinberg YY, Faustino J, Halvorson T, Lau V, Pluchino S, Vexler ZS, Carson MJ, Manor U, Peruzzotti-Jametti L, Tremblay MÈ. Vecchiarelli HA, et al. Among authors: willis c. bioRxiv [Preprint]. 2024 Oct 18:2024.10.15.618087. doi: 10.1101/2024.10.15.618087. bioRxiv. 2024. PMID: 39463930 Free PMC article. Preprint.
Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance.
Bernstock JD, Willis CM, Garcia-Segura ME, Gaude E, Anni D, Lee YJ, Thomas LW, Casey A, Vicario N, Leonardi T, Nicaise AM, Gessler FA, Izzy S, Buffelli MR, Seidlitz J, Srinivasan S, Murphy MP, Ashcroft M, Cambiaghi M, Hallenbeck JM, Peruzzotti-Jametti L. Bernstock JD, et al. bioRxiv [Preprint]. 2023 Mar 30:2023.03.29.534718. doi: 10.1101/2023.03.29.534718. bioRxiv. 2023. PMID: 37205496 Free PMC article. Preprint.
Mitochondrial reverse electron transport in myeloid cells perpetuates neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Hamel R, Krzak G, Reisz JA, Prag HA, Wu V, Xiang Y, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Vincent AE, Frezza C, Viscomi C, Marioni JC, D'Alessandro A, Takats Z, Murphy MP, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: willis cm. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574059. doi: 10.1101/2024.01.03.574059. bioRxiv. 2024. PMID: 38260262 Free PMC article. Preprint.
Metabolic Control of Smoldering Neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Hamel R, Krzak G, Pluchino S. Peruzzotti-Jametti L, et al. Front Immunol. 2021 Jun 23;12:705920. doi: 10.3389/fimmu.2021.705920. eCollection 2021. Front Immunol. 2021. PMID: 34249016 Free PMC article. Review.
The neural stem cell secretome and its role in brain repair.
Willis CM, Nicaise AM, Peruzzotti-Jametti L, Pluchino S. Willis CM, et al. Brain Res. 2020 Feb 15;1729:146615. doi: 10.1016/j.brainres.2019.146615. Epub 2019 Dec 19. Brain Res. 2020. PMID: 31863730 Free article. Review.
Stem Cells of the Aging Brain.
Nicaise AM, Willis CM, Crocker SJ, Pluchino S. Nicaise AM, et al. Front Aging Neurosci. 2020 Aug 6;12:247. doi: 10.3389/fnagi.2020.00247. eCollection 2020. Front Aging Neurosci. 2020. PMID: 32848716 Free PMC article. Review.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: willis cm. Nature. 2024 Apr;628(8006):195-203. doi: 10.1038/s41586-024-07167-9. Epub 2024 Mar 13. Nature. 2024. PMID: 38480879 Free PMC article.
1,077 results