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Malformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade.
Phillips E, van Enk S, Kildgaard S, Schlue S, Göttmann M, Jennings V, Bethke F, Müller G, Herold-Mende C, Pastor-Flores D, Schneider M, Helm D, Ostenfeld Larsen T, Goidts V. Phillips E, et al. Among authors: schneider m. Mol Oncol. 2024 Oct 27. doi: 10.1002/1878-0261.13756. Online ahead of print. Mol Oncol. 2024. PMID: 39462997 Free article.
Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity.
Lokumcu T, Iskar M, Schneider M, Helm D, Klinke G, Schlicker L, Bethke F, Müller G, Richter K, Poschet G, Phillips E, Goidts V. Lokumcu T, et al. Among authors: schneider m. ACS Nano. 2024 Jan 23;18(3):2500-2519. doi: 10.1021/acsnano.3c11427. Epub 2024 Jan 11. ACS Nano. 2024. PMID: 38207106 Free PMC article.
A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs.
Wang C, Sun M, Shao C, Schlicker L, Zhuo Y, Harim Y, Peng T, Tian W, Stöffler N, Schneider M, Helm D, Chu Y, Fu B, Jin X, Mallm JP, Mall M, Wu Y, Schulze A, Liu HK. Wang C, et al. Among authors: schneider m. NPJ Precis Oncol. 2024 Jan 26;8(1):19. doi: 10.1038/s41698-024-00500-5. NPJ Precis Oncol. 2024. PMID: 38273014 Free PMC article.
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Nůsková H, Cortizo FG, Schwenker LS, Sachsenheimer T, Diakonov EE, Tiebe M, Schneider M, Lohbeck J, Reid C, Kopp-Schneider A, Helm D, Brügger B, Miller AK, Teleman AA. Nůsková H, et al. Among authors: schneider m. J Biol Chem. 2023 Sep;299(9):105088. doi: 10.1016/j.jbc.2023.105088. Epub 2023 Jul 24. J Biol Chem. 2023. PMID: 37495107 Free PMC article.
Exploring Structural and Molecular Features of Sciatic Nerve Lesions in Diabetic Neuropathy: Unveiling Pathogenic Pathways and Targets.
Schwarz D, Marois ML, Sturm V, Peters AS, Longuespée R, Helm D, Schneider M, Eichmüller B, Hidmark AS, Fischer M, Kender Z, Schwab C, Hausser I, Weis J, Dihlmann S, Böckler D, Bendszus M, Heiland S, Herzig S, Nawroth PP, Szendroedi J, Fleming T. Schwarz D, et al. Among authors: schneider m. Diabetes. 2024 Oct 17:db240493. doi: 10.2337/db24-0493. Online ahead of print. Diabetes. 2024. PMID: 39418320
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.
Pechincha C, Groessl S, Kalis R, de Almeida M, Zanotti A, Wittmann M, Schneider M, de Campos RP, Rieser S, Brandstetter M, Schleiffer A, Müller-Decker K, Helm D, Jabs S, Haselbach D, Lemberg MK, Zuber J, Palm W. Pechincha C, et al. Among authors: schneider m. Science. 2022 Oct 7;378(6615):eabn5637. doi: 10.1126/science.abn5637. Epub 2022 Oct 7. Science. 2022. PMID: 36074822
ADAR1-mediated RNA editing promotes B cell lymphomagenesis.
Pecori R, Ren W, Pirmoradian M, Wang X, Liu D, Berglund M, Li W, Tasakis RN, Di Giorgio S, Ye X, Li X, Arnold A, Wüst S, Schneider M, Selvasaravanan KD, Fuell Y, Stafforst T, Amini RM, Sonnevi K, Enblad G, Sander B, Wahlin BE, Wu K, Zhang H, Helm D, Binder M, Papavasiliou FN, Pan-Hammarström Q. Pecori R, et al. Among authors: schneider m. iScience. 2023 May 12;26(6):106864. doi: 10.1016/j.isci.2023.106864. eCollection 2023 Jun 16. iScience. 2023. PMID: 37255666 Free PMC article.
7,410 results