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Page 1
Malformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade.
Phillips E, van Enk S, Kildgaard S, Schlue S, Göttmann M, Jennings V, Bethke F, Müller G, Herold-Mende C, Pastor-Flores D, Schneider M, Helm D, Ostenfeld Larsen T, Goidts V. Phillips E, et al. Among authors: goidts v. Mol Oncol. 2024 Oct 27. doi: 10.1002/1878-0261.13756. Online ahead of print. Mol Oncol. 2024. PMID: 39462997 Free article.
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma.
Alhalabi OT, Göttmann M, Gold MP, Schlue S, Hielscher T, Iskar M, Kessler T, Hai L, Lokumcu T, Cousins CC, Herold-Mende C, Heßling B, Horschitz S, Jabali A, Koch P, Baumgartner U, Day BW, Wick W, Sahm F, Krieg SM, Fraenkel E, Phillips E, Goidts V. Alhalabi OT, et al. Among authors: goidts v. Cancer Lett. 2024 Nov 28;605:217265. doi: 10.1016/j.canlet.2024.217265. Epub 2024 Sep 25. Cancer Lett. 2024. PMID: 39332586 Free article.
Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity.
Lokumcu T, Iskar M, Schneider M, Helm D, Klinke G, Schlicker L, Bethke F, Müller G, Richter K, Poschet G, Phillips E, Goidts V. Lokumcu T, et al. Among authors: goidts v. ACS Nano. 2024 Jan 23;18(3):2500-2519. doi: 10.1021/acsnano.3c11427. Epub 2024 Jan 11. ACS Nano. 2024. PMID: 38207106 Free PMC article.
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma.
Phillips E, Balss J, Bethke F, Pusch S, Christen S, Hielscher T, Schnölzer M, Fletcher MNC, Habel A, Tessmer C, Brenner LM, Göttmann M, Capper D, Herold-Mende C, von Deimling A, Fendt SM, Goidts V. Phillips E, et al. Among authors: goidts v. Oncogenesis. 2022 Sep 17;11(1):57. doi: 10.1038/s41389-022-00433-3. Oncogenesis. 2022. PMID: 36115843 Free PMC article.
A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma.
Alhalabi OT, Fletcher MNC, Hielscher T, Kessler T, Lokumcu T, Baumgartner U, Wittmann E, Schlue S, Göttmann M, Rahman S, Hai L, Hansen-Palmus L, Puccio L, Nakano I, Herold-Mende C, Day BW, Wick W, Sahm F, Phillips E, Goidts V. Alhalabi OT, et al. Among authors: goidts v. Neuro Oncol. 2022 Jan 5;24(1):39-51. doi: 10.1093/neuonc/noab158. Neuro Oncol. 2022. PMID: 34232320 Free PMC article.
Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Wang J, Cheng P, Pavlyukov MS, Yu H, Zhang Z, Kim SH, Minata M, Mohyeldin A, Xie W, Chen D, Goidts V, Frett B, Hu W, Li H, Shin YJ, Lee Y, Nam DH, Kornblum HI, Wang M, Nakano I. Wang J, et al. Among authors: goidts v. J Clin Invest. 2020 Nov 2;130(11):6187. doi: 10.1172/JCI144618. J Clin Invest. 2020. PMID: 33044225 Free PMC article. No abstract available.
Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Wang J, Cheng P, Pavlyukov MS, Yu H, Zhang Z, Kim SH, Minata M, Mohyeldin A, Xie W, Chen D, Goidts V, Frett B, Hu W, Li H, Shin YJ, Lee Y, Nam DH, Kornblum HI, Wang M, Nakano I. Wang J, et al. Among authors: goidts v. J Clin Invest. 2020 Sep 1;130(9):5027. doi: 10.1172/JCI142404. J Clin Invest. 2020. PMID: 32870163 Free PMC article. No abstract available.
Intratumoral spatial heterogeneity of BTK kinomic activity dictates distinct therapeutic response within a single glioblastoma tumor.
Ibrahim AN, Yamashita D, Anderson JC, Abdelrashid M, Alwakeal A, Estevez-Ordonez D, Komarova S, Markert JM, Goidts V, Willey CD, Nakano I. Ibrahim AN, et al. Among authors: goidts v. J Neurosurg. 2019 Oct 18;133(6):1683-1694. doi: 10.3171/2019.7.JNS191376. Print 2020 Dec 1. J Neurosurg. 2019. PMID: 31628288 Free PMC article.
34 results