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APC truncating mutations in Middle Eastern Population: Tankyrase inhibitor is an effective strategy to sensitize APC mutant CRC To 5-FU chemotherapy.
Siraj AK, Kumar Parvathareddy S, Pratheeshkumar P, Padmaja Divya S, Ahmed SO, Melosantos R, Begum R, Concepcion RMJA, Al-Sanea N, Ashari LH, Abduljabbar A, Al-Dayel F, Al-Kuraya KS. Siraj AK, et al. Among authors: begum r. Biomed Pharmacother. 2020 Jan;121:109572. doi: 10.1016/j.biopha.2019.109572. Epub 2019 Nov 5. Biomed Pharmacother. 2020. PMID: 31704613 Free article.
Overexpression of the pro-protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling.
Poyil PK, Siraj AK, Padmaja D, Parvathareddy SK, Diaz R, Thangavel S, Begum R, Haqawi W, Al-Mohanna FH, Al-Sobhi SS, Al-Dayel F, Al-Kuraya KS. Poyil PK, et al. Among authors: begum r. Mol Oncol. 2023 Jul;17(7):1324-1342. doi: 10.1002/1878-0261.13396. Epub 2023 Feb 27. Mol Oncol. 2023. PMID: 36799665 Free PMC article.
PLK1 and PARP positively correlate in Middle Eastern breast cancer and their combined inhibition overcomes PARP inhibitor resistance in triple negative breast cancer.
Siraj AK, Poyil PK, Padmaja D, Parvathareddy SK, Alobaisi K, Thangavel S, Diaz R, Begum R, Almalik O, Al-Dayel F, Al-Kuraya KS. Siraj AK, et al. Among authors: begum r. Front Oncol. 2024 Jan 3;13:1286585. doi: 10.3389/fonc.2023.1286585. eCollection 2023. Front Oncol. 2024. PMID: 38234395 Free PMC article.
PLK1 and FoxM1 expressions positively correlate in papillary thyroid carcinoma and their combined inhibition results in synergistic anti-tumor effects.
Poyil PK, Siraj AK, Padmaja D, Parvathareddy SK, Thangavel S, Alobaisi K, Diaz R, Begum R, Haqawi W, Al-Sobhi SS, Al-Dayel F, Al-Kuraya KS. Poyil PK, et al. Among authors: begum r. Mol Oncol. 2024 Mar;18(3):691-706. doi: 10.1002/1878-0261.13610. Epub 2024 Feb 15. Mol Oncol. 2024. PMID: 38361222 Free PMC article.
Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer.
Pratheeshkumar P, Siraj AK, Divya SP, Parvathareddy SK, Siraj S, Diaz R, Begum R, Al-Sobhi SS, Al-Dayel F, Al-Kuraya KS. Pratheeshkumar P, et al. Among authors: begum r. Cancers (Basel). 2021 Jan 7;13(2):185. doi: 10.3390/cancers13020185. Cancers (Basel). 2021. PMID: 33430300 Free PMC article.
498 results