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Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
Metaferia B, Cellmer T, Dunkelberger EB, Li Q, Henry ER, Hofrichter J, Staton D, Hsieh MM, Conrey AK, Tisdale JF, Chatterjee AK, Thein SL, Eaton WA. Metaferia B, et al. Among authors: henry er. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2210779119. doi: 10.1073/pnas.2210779119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161945 Free PMC article.
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Henry ER, Cellmer T, Dunkelberger EB, Metaferia B, Hofrichter J, Li Q, Ostrowski D, Ghirlando R, Louis JM, Moutereau S, Galactéros F, Thein SL, Bartolucci P, Eaton WA. Henry ER, et al. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15018-15027. doi: 10.1073/pnas.1922004117. Epub 2020 Jun 11. Proc Natl Acad Sci U S A. 2020. PMID: 32527859 Free PMC article.
Voxelotor treatment of a patient with sickle cell disease and very severe anemia.
Shet AS, Mendelsohn L, Harper J, Ostrowski D, Henry ER, Gwaabe E, Nichols J, Alayash AI, Eaton WA, Thein SL. Shet AS, et al. Among authors: henry er. Am J Hematol. 2019 Apr;94(4):E88-E90. doi: 10.1002/ajh.25389. Epub 2019 Jan 8. Am J Hematol. 2019. PMID: 30592074 Free PMC article. No abstract available.
60 results