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Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling.
Wu B, Bennett HM, Ye X, Sridhar A, Eidenschenk C, Everett C, Nazarova EV, Chen HH, Kim IK, Deangelis M, Owen LA, Chen C, Lau J, Shi M, Lund JM, Xavier-Magalhães A, Patel N, Liang Y, Modrusan Z, Darmanis S. Wu B, et al. Among authors: liang y. Nat Commun. 2024 Oct 23;15(1):9146. doi: 10.1038/s41467-024-53227-z. Nat Commun. 2024. PMID: 39443484 Free PMC article.
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Dominguez CX, Müller S, Keerthivasan S, Koeppen H, Hung J, Gierke S, Breart B, Foreman O, Bainbridge TW, Castiglioni A, Senbabaoglu Y, Modrusan Z, Liang Y, Junttila MR, Klijn C, Bourgon R, Turley SJ. Dominguez CX, et al. Among authors: liang y. Cancer Discov. 2020 Feb;10(2):232-253. doi: 10.1158/2159-8290.CD-19-0644. Epub 2019 Nov 7. Cancer Discov. 2020. PMID: 31699795
Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components.
Chen H, Durinck S, Patel H, Foreman O, Mesh K, Eastham J, Caothien R, Newman RJ, Roose-Girma M, Darmanis S, Warming S, Lattanzi A, Liang Y, Haley B. Chen H, et al. Among authors: liang y. Mol Ther Methods Clin Dev. 2022 Nov 1;27:431-449. doi: 10.1016/j.omtm.2022.10.016. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36419469 Free PMC article.
Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.
Yun J, Hansen S, Morris O, Madden DT, Libeu CP, Kumar AJ, Wehrfritz C, Nile AH, Zhang Y, Zhou L, Liang Y, Modrusan Z, Chen MB, Overall CC, Garfield D, Campisi J, Schilling B, Hannoush RN, Jasper H. Yun J, et al. Among authors: liang y. Nat Commun. 2023 Jan 11;14(1):156. doi: 10.1038/s41467-022-35487-9. Nat Commun. 2023. PMID: 36631445 Free PMC article.
Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients.
Kuo J, Uzunovic J, Jacobson A, Dourado M, Gierke S, Rajendram M, Keilberg D, Mar J, Stekol E, Curry J, Verstraete S, Lund J, Liang Y, Tamburini FB, Omattage NS, Masureel M, Rutherford ST, Hackos DH, Tan MW, Byrd AL, Keir ME, Skippington E, Storek KM. Kuo J, et al. Among authors: liang y. J Crohns Colitis. 2024 Aug 6;18(7):985-1001. doi: 10.1093/ecco-jcc/jjae016. J Crohns Colitis. 2024. PMID: 38267224 Free PMC article.
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity.
Herault A, Mak J, de la Cruz-Chuh J, Dillon MA, Ellerman D, Go M, Cosino E, Clark R, Carson E, Yeung S, Pichery M, Gador M, Chiang EY, Wu J, Liang Y, Modrusan Z, Gampa G, Sudhamsu J, Kemball CC, Cheung V, Nguyen TTT, Seshasayee D, Piskol R, Totpal K, Yu SF, Lee G, Kozak KR, Spiess C, Walsh KB. Herault A, et al. Among authors: liang y. Cancer Immunol Immunother. 2024 Aug 8;73(10):209. doi: 10.1007/s00262-024-03795-2. Cancer Immunol Immunother. 2024. PMID: 39112670 Free PMC article.
Gut cytokines modulate olfaction through metabolic reprogramming of glia.
Cai XT, Li H, Borch Jensen M, Maksoud E, Borneo J, Liang Y, Quake SR, Luo L, Haghighi P, Jasper H. Cai XT, et al. Among authors: liang y. Nature. 2021 Aug;596(7870):97-102. doi: 10.1038/s41586-021-03756-0. Epub 2021 Jul 21. Nature. 2021. PMID: 34290404 Free PMC article.
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