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Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Among authors: shultz ld. Mol Metab. 2024 Oct 20;90:102050. doi: 10.1016/j.molmet.2024.102050. Online ahead of print. Mol Metab. 2024. PMID: 39433176 Free PMC article.
Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE; HPAP Consortium; Parker SCJ, Powers AC, Brissova M. Walker JT, et al. Among authors: shultz ld. Nature. 2023 Dec;624(7992):621-629. doi: 10.1038/s41586-023-06693-2. Epub 2023 Dec 4. Nature. 2023. PMID: 38049589 Free PMC article.
Humanized mouse models for immuno-oncology research.
Chuprin J, Buettner H, Seedhom MO, Greiner DL, Keck JG, Ishikawa F, Shultz LD, Brehm MA. Chuprin J, et al. Among authors: shultz ld. Nat Rev Clin Oncol. 2023 Mar;20(3):192-206. doi: 10.1038/s41571-022-00721-2. Epub 2023 Jan 12. Nat Rev Clin Oncol. 2023. PMID: 36635480 Free PMC article. Review.
Clathrin light chain-conjugated drug delivery for cancer.
Jung S, Jiang L, Zhao J, Shultz LD, Greiner DL, Bae M, Li X, Ordikhani F, Kuai R, Joseph J, Kasinath V, Elmaleh DR, Abdi R. Jung S, et al. Among authors: shultz ld. Bioeng Transl Med. 2022 Nov 28;8(1):e10273. doi: 10.1002/btm2.10273. eCollection 2023 Jan. Bioeng Transl Med. 2022. PMID: 36684105 Free PMC article.
Development of New Diffuse Large B Cell Lymphoma Mouse Models.
Mehdi SH, Xu YZ, Shultz LD, Kim E, Lee YG, Kendrick S, Yoon D. Mehdi SH, et al. Among authors: shultz ld. Cancers (Basel). 2024 Aug 29;16(17):3006. doi: 10.3390/cancers16173006. Cancers (Basel). 2024. PMID: 39272864 Free PMC article.
464 results