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Efficacy, safety and tolerability of GSK3858279, an anti-CCL17 monoclonal antibody and analgesic, in healthy volunteers and patients with knee osteoarthritis pain: a phase I, randomised, double-blind, placebo-controlled, proof-of-mechanism and proof-of-concept study.
Nijjar JS, Abbott-Banner K, Alvarez Y, Aston N, Bass D, Bentley JH, Ellis J, Ellson C, Emery EC, Feeney M, Fernando D, Inman D, Kaur R, Modis LK, Munoz Vicente S, Muya C, Nistala K, Panoilia E, Ray R, Siederer S, Smith JE, Weir L, Wisniacki N. Nijjar JS, et al. Among authors: feeney m. Ann Rheum Dis. 2024 Oct 17:ard-2023-225434. doi: 10.1136/ard-2023-225434. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39419538 Free article.
CCL17 in Inflammation and Pain.
Lee KM, Jarnicki A, Achuthan A, Fleetwood AJ, Anderson GP, Ellson C, Feeney M, Modis LK, Smith JE, Hamilton JA, Cook A. Lee KM, et al. Among authors: feeney m. J Immunol. 2020 Jul 1;205(1):213-222. doi: 10.4049/jimmunol.2000315. Epub 2020 May 27. J Immunol. 2020. PMID: 32461237
Depletion of LAG-3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781.
Ellis J, J B Marks D, Srinivasan N, Barrett C, Hopkins TG, Richards A, Fuhr R, Albayaty M, Coenen M, Liefaard L, Leavens K, Nevin KL, Tang S, Hughes SA, Fortunato L, Edwards K, Cui Y, Anselm R, Delves CJ, Charles E, Feeney M, Webb TM, Brett SJ, Schmidt TS, Stone J, Savage COS, Wisniacki N, Tarzi RM. Ellis J, et al. Among authors: feeney m. Clin Pharmacol Ther. 2021 May;109(5):1293-1303. doi: 10.1002/cpt.2091. Epub 2020 Nov 24. Clin Pharmacol Ther. 2021. PMID: 33113155 Free PMC article. Clinical Trial.
Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controlled trials.
Choy EH, Bendit M, McAleer D, Liu F, Feeney M, Brett S, Zamuner S, Campanile A, Toso J. Choy EH, et al. Among authors: feeney m. Arthritis Res Ther. 2013 Sep 24;15(5):R132. doi: 10.1186/ar4312. Arthritis Res Ther. 2013. PMID: 24286335 Free PMC article. Clinical Trial.
Discovery of functionally distinct anti-C7 monoclonal antibodies and stratification of anti-nicotinic AChR positive Myasthenia Gravis patients.
Lekova E, Zelek WM, Gower D, Spitzfaden C, Osuch IH, John-Morris E, Stach L, Gormley D, Sanderson A, Bridges A, Wear ER, Petit-Frere S, Burden MN, Priest R, Wattam T, Kitchen SJ, Feeney M, Davis S, Morgan BP, Nichols EM. Lekova E, et al. Among authors: feeney m. Front Immunol. 2022 Sep 5;13:968206. doi: 10.3389/fimmu.2022.968206. eCollection 2022. Front Immunol. 2022. PMID: 36148231 Free PMC article.
Broadly inhibitory antibodies to severe malaria virulence proteins.
Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Bol S, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, López-Gutiérrez B, Sanz S, Bancells C, Fernández-Quintero ML, Loeffler JR, Ferguson JA, Lee WH, Martin GM, Theander TG, Lusingu JPA, Minja DTR, Ssewanyana I, Feeney ME, Greenhouse B, Ward AB, Bernabeu M, Pancera M, Turner L, Bunnik EM, Lavstsen T. Reyes RA, et al. Among authors: feeney me. Nature. 2024 Nov 20. doi: 10.1038/s41586-024-08220-3. Online ahead of print. Nature. 2024. PMID: 39567685
Food Allergy Test-Guided Dietary Advice for Children With Atopic Dermatitis: A Consensus Study.
Garside L, Boyle R, Meyer R, Skypala I, Allen H, Beattie P, Dempsey J, Doyle M, Evans-Howells H, Feeney M, Ludman S, Marrs T, Ravenscroft J, Stiefel G, Umasunthar T, Vyas D, Yerlett N, Walsh J, Brown SJ, Ridd MJ. Garside L, et al. Among authors: feeney m. Pediatr Dermatol. 2024 Nov 11. doi: 10.1111/pde.15807. Online ahead of print. Pediatr Dermatol. 2024. PMID: 39528241
363 results