Liu X - Search Results

1

"Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency.

Xu S, Wang S, Zhou Y, Foley N, Sun L, Walsham L, Tang K, Shi D, Shi X, Zhang Z, Jiang X, Gao S, Liu X, Pannecouque C, Goldstone DC, Dick A, Zhan P. Xu S, et al. Among authors: liu x. J Med Chem. 2024 Nov 14;67(21):19057-19076. doi: 10.1021/acs.jmedchem.4c01544. Epub 2024 Oct 17. J Med Chem. 2024. PMID: 39418501

2

Synthesis and anti-HIV evaluation of the novel 2-(m-chlorobenzyl)-4-substituted-7-methyl-1, 1, 3-trioxo-pyrazolo[4, 5-e] [1, 2, 4]thiadiazines.

Yan RZ, Liu XY, Xu WF, Pannecouque C, Witvrouw M, De Clercq E. Yan RZ, et al. Arch Pharm Res. 2006 Nov;29(11):957-62. doi: 10.1007/BF02969278. Arch Pharm Res. 2006. PMID: 17146963

3

Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs.

Wu J, Liu X, Cheng X, Cao Y, Wang D, Li Z, Xu W, Pannecouque C, Witvrouw M, De Clercq E. Wu J, et al. Among authors: liu x. Molecules. 2007 Aug 22;12(8):2003-16. doi: 10.3390/12082003. Molecules. 2007. PMID: 17960101 Free PMC article.

4

Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs).

Lin Y, Liu X, Yan R, Li J, Pannecouque C, Witvrouw M, De Clercq E. Lin Y, et al. Among authors: liu x. Bioorg Med Chem. 2008 Jan 1;16(1):157-63. doi: 10.1016/j.bmc.2007.10.013. Epub 2007 Oct 10. Bioorg Med Chem. 2008. PMID: 17964796 Free article.

5

Synthesis and anti-HIV activity evaluation of novel 2,4-disubstituted 7-methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo-[4,5-e][1,2]thiadiazines.

Liu XY, Yan RZ, Wang Y, Zhan P, De Clercq E, Pannecouque C, Witvrouw M, Molina MT, Vega S. Liu XY, et al. Arch Pharm (Weinheim). 2008 Apr;341(4):216-22. doi: 10.1002/ardp.200700216. Arch Pharm (Weinheim). 2008. PMID: 18266290

6

Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives.

Zhan P, Liu X, De Clercq E. Zhan P, et al. Among authors: liu x. Curr Med Chem. 2008;15(15):1529-40. doi: 10.2174/092986708784638898. Curr Med Chem. 2008. PMID: 18537628 Review.

7

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Zhan P, Liu X, Cao Y, Wang Y, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: liu x. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5368-71. doi: 10.1016/j.bmcl.2008.09.055. Epub 2008 Sep 18. Bioorg Med Chem Lett. 2008. PMID: 18824350

8

Recent advances in the research of HIV-1 RNase H inhibitors.

Yu F, Liu X, Zhan P, De Clercq E. Yu F, et al. Among authors: liu x. Mini Rev Med Chem. 2008 Oct;8(12):1243-51. doi: 10.2174/138955708786141052. Mini Rev Med Chem. 2008. PMID: 18855738 Review.

9

Capsid (CA) protein as a novel drug target: recent progress in the research of HIV-1 CA inhibitors.

Zhang J, Liu X, De Clercq E. Zhang J, et al. Among authors: liu x. Mini Rev Med Chem. 2009 Apr;9(4):510-8. doi: 10.2174/138955709787847958. Mini Rev Med Chem. 2009. PMID: 19356128 Review.

10

Designed multiple ligands: an emerging anti-HIV drug discovery paradigm.

Zhan P, Liu X. Zhan P, et al. Among authors: liu x. Curr Pharm Des. 2009;15(16):1893-917. doi: 10.2174/138161209788453266. Curr Pharm Des. 2009. PMID: 19519431 Review.

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