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Knockdown of Ketohexokinase Versus Inhibition of Its Kinase Activity Exert Divergent Effects on Fructose Metabolism.
Park SH, Fadhul T, Conroy LR, Clarke HA, Sun RC, Wallenius K, Boucher J, O'Mahony G, Boianelli A, Persson M, Jung S, Jang C, Loria AS, Martinez GJ, Kipp ZA, Bates EA, Hinds TD Jr, Divanovic S, Softic S. Park SH, et al. Among authors: wallenius k. JCI Insight. 2024 Oct 17:e184396. doi: 10.1172/jci.insight.184396. Online ahead of print. JCI Insight. 2024. PMID: 39418102 Free article.
Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonist.
Haggag AZ, Xu J, Butcher L, Pagnussat S, Davies G, Lundqvist S, Wang W, Van Zuydam N, Nelander K, Jha A, Yu H, Boianelli A, Lindmark B, Ollerstam A, Sun X, Wang F, Pan X, Liu H, Chen W, Xu J, Wallenius K, Zhou J. Haggag AZ, et al. Among authors: wallenius k. Diabetes Obes Metab. 2024 Nov 4. doi: 10.1111/dom.16047. Online ahead of print. Diabetes Obes Metab. 2024. PMID: 39495140
Involvement of the metabolic sensor GPR81 in cardiovascular control.
Wallenius K, Thalén P, Björkman JA, Johannesson P, Wiseman J, Böttcher G, Fjellström O, Oakes ND. Wallenius K, et al. JCI Insight. 2017 Oct 5;2(19):e92564. doi: 10.1172/jci.insight.92564. JCI Insight. 2017. PMID: 28978803 Free PMC article.
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.
Liu C, Schönke M, Spoorenberg B, Lambooij JM, van der Zande HJP, Zhou E, Tushuizen ME, Andreasson AC, Park A, Oldham S, Uhrbom M, Ahlstedt I, Ikeda Y, Wallenius K, Peng XR, Guigas B, Boon MR, Wang Y, Rensen PCN. Liu C, et al. Among authors: wallenius k. Elife. 2023 Jan 17;12:e83075. doi: 10.7554/eLife.83075. Elife. 2023. PMID: 36648330 Free PMC article.
Liver-derived IGF-I regulates GH secretion at the pituitary level in mice.
Wallenius K, Sjögren K, Peng XD, Park S, Wallenius V, Liu JL, Umaerus M, Wennbo H, Isaksson O, Frohman L, Kineman R, Ohlsson C, Jansson JO. Wallenius K, et al. Among authors: wallenius v. Endocrinology. 2001 Nov;142(11):4762-70. doi: 10.1210/endo.142.11.8478. Endocrinology. 2001. PMID: 11606442
78 results