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Page 1
Targetable treatment resistance in thyroid cancer with clonal hematopoiesis.
Tiedje V, Vela PS, Yang JL, Untch BR, Boucai L, Stonestrom AJ, Costa AB, Expósito SF, Srivastava A, Kerpelev M, Greenberg J, Wereski M, Kulick A, Chen K, Qin T, Im SY, Krishnan A, Martinez Benitez AR, Pluvinet R, Sahin M, Menghrajani K, Krishnamoorthy GP, de Stanchina E, Zehir A, Satija R, Knauf J, Bowman RL, Esteller M, Devlin S, Berger MF, Koche RP, Fagin JA, Levine RL. Tiedje V, et al. Among authors: koche rp. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617685. doi: 10.1101/2024.10.10.617685. bioRxiv. 2024. PMID: 39415999 Free PMC article. Preprint.
Correction: SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.
Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga Á, Rudin CM. Redin E, et al. Among authors: koche rp. J Hematol Oncol. 2024 Sep 29;17(1):89. doi: 10.1186/s13045-024-01609-7. J Hematol Oncol. 2024. PMID: 39343962 Free PMC article. No abstract available.
TGF-β and RAS jointly unmask primed enhancers to drive metastasis.
Lee JH, Sánchez-Rivera FJ, He L, Basnet H, Chen FX, Spina E, Li L, Torner C, Chan JE, Yarlagadda DVK, Park JS, Sussman C, Rudin CM, Lowe SW, Tammela T, Macias MJ, Koche RP, Massagué J. Lee JH, et al. Among authors: koche rp. Cell. 2024 Oct 31;187(22):6182-6199.e29. doi: 10.1016/j.cell.2024.08.014. Epub 2024 Sep 6. Cell. 2024. PMID: 39243762
SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.
Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga Á, Rudin CM. Redin E, et al. Among authors: koche rp. J Hematol Oncol. 2024 Jul 30;17(1):58. doi: 10.1186/s13045-024-01572-3. J Hematol Oncol. 2024. PMID: 39080761 Free PMC article.
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation.
Quintanal-Villalonga A, Kawasaki K, Redin E, Uddin F, Rakhade S, Durani V, Sabet A, Shafer M, Karthaus WR, Zaidi S, Zhan YA, Manoj P, Sridhar H, Kinyua D, Zhong H, Mello BP, Ciampricotti M, Bhanot UK, Linkov I, Qiu J, Patel RA, Morrissey C, Mehta S, Barnes J, Haffner MC, Socci ND, Koche RP, de Stanchina E, Molina-Pinelo S, Salehi S, Yu HA, Chan JM, Rudin CM. Quintanal-Villalonga A, et al. Among authors: koche rp. Signal Transduct Target Ther. 2024 Jul 26;9(1):189. doi: 10.1038/s41392-024-01908-y. Signal Transduct Target Ther. 2024. PMID: 39054323 Free PMC article.
Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis.
Zhuang X, Wang Q, Joost S, Ferrena A, Humphreys DT, Li Z, Blum M, Bastl K, Ding S, Landais Y, Zhan Y, Zhao Y, Chaligne R, Lee JH, Carrasco SE, Bhanot UK, Koche RP, Bott MJ, Katajisto P, Soto-Feliciano YM, Pisanic T, Thomas T, Zheng D, Wong ES, Tammela T. Zhuang X, et al. Among authors: koche rp. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.600305. doi: 10.1101/2024.06.23.600305. bioRxiv. 2024. PMID: 38979280 Free PMC article. Preprint.
A nucleosome switch primes Hepatitis B Virus infection.
Prescott NA, Mansisidor A, Bram Y, Biaco T, Rendleman J, Faulkner SC, Lemmon AA, Lim C, Hamard PJ, Koche RP, Risca VI, Schwartz RE, David Y. Prescott NA, et al. Among authors: koche rp. bioRxiv [Preprint]. 2024 Jun 12:2023.03.03.531011. doi: 10.1101/2023.03.03.531011. bioRxiv. 2024. PMID: 38915612 Free PMC article. Preprint.
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells.
Waarts MR, Mowla S, Boileau M, Martinez Benitez AR, Sango J, Bagish M, Fernández-Maestre I, Shan Y, Eisman SE, Park YC, Wereski M, Csete I, O'Connor K, Romero-Vega AC, Miles LA, Xiao W, Wu X, Koche RP, Armstrong SA, Shih AH, Papapetrou EP, Butler JM, Cai SF, Bowman RL, Levine RL. Waarts MR, et al. Among authors: koche rp. Cancer Discov. 2024 Oct 4;14(10):1860-1878. doi: 10.1158/2159-8290.CD-23-1092. Cancer Discov. 2024. PMID: 38819218
66 results