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Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses.
Axelsson J, LeBlanc D, Shojaeisaadi H, Meier MJ, Fitzgerald DM, Nachmanson D, Carlson J, Golubeva A, Higgins J, Smith T, Lo FY, Pilsner R, Williams A, Salk J, Marchetti F, Yauk C. Axelsson J, et al. Among authors: meier mj. Sci Rep. 2024 Oct 8;14(1):23134. doi: 10.1038/s41598-024-73587-2. Sci Rep. 2024. PMID: 39379474 Free PMC article.
In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice.
Meier MJ, O'Brien JM, Beal MA, Allan B, Yauk CL, Marchetti F. Meier MJ, et al. Environ Health Perspect. 2017 Jan;125(1):82-88. doi: 10.1289/EHP211. Epub 2016 Jul 22. Environ Health Perspect. 2017. PMID: 27448386 Free PMC article.
CONCLUSION: In utero exposure to environmental mutagens contributes to somatic and germline mosaicism, permanently affecting both the genetic health of the F1 and the population gene pool. Citation: Meier MJ, O'Brien JM, Beal MA, Allan B, Yauk CL, Marchetti F. 2017. …
CONCLUSION: In utero exposure to environmental mutagens contributes to somatic and germline mosaicism, permanently affecting both the geneti …
High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization.
Rowan-Carroll A, Reardon A, Leingartner K, Gagné R, Williams A, Meier MJ, Kuo B, Bourdon-Lacombe J, Moffat I, Carrier R, Nong A, Lorusso L, Ferguson SS, Atlas E, Yauk C. Rowan-Carroll A, et al. Among authors: meier mj. Toxicol Sci. 2021 May 27;181(2):199-214. doi: 10.1093/toxsci/kfab039. Toxicol Sci. 2021. PMID: 33772556
R-ODAF: Omics data analysis framework for regulatory application.
Verheijen MC, Meier MJ, Asensio JO, Gant TW, Tong W, Yauk CL, Caiment F. Verheijen MC, et al. Among authors: meier mj. Regul Toxicol Pharmacol. 2022 Jun;131:105143. doi: 10.1016/j.yrtph.2022.105143. Epub 2022 Mar 3. Regul Toxicol Pharmacol. 2022. PMID: 35247516 Free article.
85 results