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NAT10-mediated mRNA N4-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia.
Zhang S, Huang F, Wang Y, Long Y, Li Y, Kang Y, Gao W, Zhang X, Wen Y, Wang Y, Pan L, Xia Y, Yang Z, Yang Y, Mo H, Li B, Hu J, Song Y, Zhang S, Dong S, Du X, Li Y, Liu Y, Liao W, Gao Y, Zhang Y, Chen H, Liang Y, Chen J, Weng H, Huang H. Zhang S, et al. Among authors: huang f, huang h. Nat Cell Biol. 2024 Nov 6. doi: 10.1038/s41556-024-01548-y. Online ahead of print. Nat Cell Biol. 2024. PMID: 39506072
N6 -methyladenosine Steers RNA Metabolism and Regulation in Cancer.
Dong S, Wu Y, Liu Y, Weng H, Huang H. Dong S, et al. Among authors: huang h. Cancer Commun (Lond). 2021 Jul;41(7):538-559. doi: 10.1002/cac2.12161. Epub 2021 May 6. Cancer Commun (Lond). 2021. PMID: 33955720 Free PMC article. Review.
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia.
Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Chen Z, et al. Among authors: huang h. Sci Transl Med. 2023 Mar 29;15(689):eabq8513. doi: 10.1126/scitranslmed.abq8513. Epub 2023 Mar 29. Sci Transl Med. 2023. PMID: 36989375 Free PMC article.
The roles and implications of RNA m6A modification in cancer.
Deng X, Qing Y, Horne D, Huang H, Chen J. Deng X, et al. Among authors: huang h. Nat Rev Clin Oncol. 2023 Aug;20(8):507-526. doi: 10.1038/s41571-023-00774-x. Epub 2023 May 23. Nat Rev Clin Oncol. 2023. PMID: 37221357 Review.
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