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Page 1
p38α kinase governs muscle strength through PGC1α in mice.
Herrera-Melle L, Cicuéndez B, López JA, Dumesic PA, Wilensky SE, Rodríguez E, Leiva-Vega L, Caballero A, León M, Vázquez J, Spiegelman BM, Folgueira C, Mora A, Sabio G. Herrera-Melle L, et al. Among authors: rodriguez e. Acta Physiol (Oxf). 2024 Nov;240(11):e14234. doi: 10.1111/apha.14234. Epub 2024 Oct 3. Acta Physiol (Oxf). 2024. PMID: 39361268
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: rodriguez e. EMBO Rep. 2024 Jun;25(6):2635-2661. doi: 10.1038/s44319-024-00149-y. Epub 2024 May 10. EMBO Rep. 2024. PMID: 38730210 Free PMC article.
Remodeling p38 signaling in muscle controls locomotor activity via IL-15.
Folgueira C, Herrera-Melle L, López JA, Galvan-Alvarez V, Martin-Rincon M, Cuartero MI, García-Culebras A, Dumesic PA, Rodríguez E, Leiva-Vega L, León M, Porteiro B, Iglesias C, Torres JL, Hernández-Cosido L, Bonacasa C, Marcos M, Moro MÁ, Vázquez J, Calbet JAL, Spiegelman BM, Mora A, Sabio G. Folgueira C, et al. Among authors: rodriguez e. Sci Adv. 2024 Aug 16;10(33):eadn5993. doi: 10.1126/sciadv.adn5993. Epub 2024 Aug 14. Sci Adv. 2024. PMID: 39141732 Free PMC article.
p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.
Matesanz N, Nikolic I, Leiva M, Pulgarín-Alfaro M, Santamans AM, Bernardo E, Mora A, Herrera-Melle L, Rodríguez E, Beiroa D, Caballero A, Martín-García E, Acín-Pérez R, Hernández-Cosido L, Leiva-Vega L, Torres JL, Centeno F, Nebreda AR, Enríquez JA, Nogueiras R, Marcos M, Sabio G. Matesanz N, et al. Among authors: rodriguez e. PLoS Biol. 2018 Jul 6;16(7):e2004455. doi: 10.1371/journal.pbio.2004455. eCollection 2018 Jul. PLoS Biol. 2018. PMID: 29979672 Free PMC article.
Adiponectin accounts for gender differences in hepatocellular carcinoma incidence.
Manieri E, Herrera-Melle L, Mora A, Tomás-Loba A, Leiva-Vega L, Fernández DI, Rodríguez E, Morán L, Hernández-Cosido L, Torres JL, Seoane LM, Cubero FJ, Marcos M, Sabio G. Manieri E, et al. Among authors: rodriguez e. J Exp Med. 2019 May 6;216(5):1108-1119. doi: 10.1084/jem.20181288. Epub 2019 Apr 3. J Exp Med. 2019. PMID: 30944152 Free PMC article.
p38γ is essential for cell cycle progression and liver tumorigenesis.
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Tomás-Loba A, et al. Among authors: rodriguez e. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. Nature. 2019. PMID: 30971822
Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism.
Crespo M, Gonzalez-Teran B, Nikolic I, Mora A, Folgueira C, Rodríguez E, Leiva-Vega L, Pintor-Chocano A, Fernández-Chacón M, Ruiz-Garrido I, Cicuéndez B, Tomás-Loba A, A-Gonzalez N, Caballero-Molano A, Beiroa D, Hernández-Cosido L, Torres JL, Kennedy NJ, Davis RJ, Benedito R, Marcos M, Nogueiras R, Hidalgo A, Matesanz N, Leiva M, Sabio G. Crespo M, et al. Among authors: rodriguez e. Elife. 2020 Dec 8;9:e59258. doi: 10.7554/eLife.59258. Elife. 2020. PMID: 33287957 Free PMC article.
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.
Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G. Santamans AM, et al. Among authors: rodriguez e. PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov. PLoS Biol. 2021. PMID: 34758018 Free PMC article.
MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Romero-Becerra R, Mora A, Manieri E, Nikolic I, Santamans AM, Montalvo-Romeral V, Cruz FM, Rodríguez E, León M, Leiva-Vega L, Sanz L, Bondía V, Filgueiras-Rama D, Jiménez-Borreguero LJ, Jalife J, Gonzalez-Teran B, Sabio G. Romero-Becerra R, et al. Among authors: rodriguez e. Elife. 2022 Aug 16;11:e75250. doi: 10.7554/eLife.75250. Elife. 2022. PMID: 35971771 Free PMC article.
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension.
Santamans AM, Cicuéndez B, Mora A, Villalba-Orero M, Rajlic S, Crespo M, Vo P, Jerome M, Macías Á, López JA, Leiva M, Rocha SF, León M, Rodríguez E, Leiva L, Pintor Chocano A, García Lunar I, García-Álvarez A, Hernansanz-Agustín P, Peinado VI, Barberá JA, Ibañez B, Vázquez J, Spinelli JB, Daiber A, Oliver E, Sabio G. Santamans AM, et al. Among authors: rodriguez e. Sci Adv. 2024 Jan 19;10(3):eadk6524. doi: 10.1126/sciadv.adk6524. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241373 Free PMC article.
3,931 results