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Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5E)-(8R)-(14Z)-Mycothiazole Analogue.
Gerke JA, Odron SF, Kim J, Dutta N, Clarke JG, Media J, Coppage DA, Oorloff M, Alcala A, Garcia G, Kang MEF, Gerke CL, Peterson JC, Morris JD, Higuchi-Sanabria R, Valeriote FA, Crews P, Johnson TA. Gerke JA, et al. J Nat Prod. 2024 Oct 25;87(10):2523-2529. doi: 10.1021/acs.jnatprod.4c00691. Epub 2024 Sep 30. J Nat Prod. 2024. PMID: 39348562
Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging.
Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Castro Torres T, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. Dutta N, et al. Among authors: gerke ja. bioRxiv [Preprint]. 2023 Nov 27:2023.11.27.568896. doi: 10.1101/2023.11.27.568896. bioRxiv. 2023. PMID: 38077060 Free PMC article. Preprint.
Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging.
Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Kim J, Torres TC, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. Dutta N, et al. Among authors: gerke ja. Geroscience. 2024 Dec;46(6):6009-6028. doi: 10.1007/s11357-024-01144-w. Epub 2024 Apr 3. Geroscience. 2024. PMID: 38570396 Free PMC article.