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An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major.
Iniguez E, Schocker NS, Subramaniam K, Portillo S, Montoya AL, Al-Salem WS, Torres CL, Rodriguez F, Moreira OC, Acosta-Serrano A, Michael K, Almeida IC, Maldonado RA. Iniguez E, et al. Among authors: maldonado ra. PLoS Negl Trop Dis. 2017 Oct 25;11(10):e0006039. doi: 10.1371/journal.pntd.0006039. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 29069089 Free PMC article.
Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.
Herrera LJ, Brand S, Santos A, Nohara LL, Harrison J, Norcross NR, Thompson S, Smith V, Lema C, Varela-Ramirez A, Gilbert IH, Almeida IC, Maldonado RA. Herrera LJ, et al. Among authors: maldonado ra. PLoS Negl Trop Dis. 2016 Apr 29;10(4):e0004540. doi: 10.1371/journal.pntd.0004540. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27128971 Free PMC article.
Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia.
Mendez TL, De Chatterjee A, Duarte TT, Gazos-Lopes F, Robles-Martinez L, Roy D, Sun J, Maldonado RA, Roychowdhury S, Almeida IC, Das S. Mendez TL, et al. Among authors: maldonado ra. J Biol Chem. 2013 Jun 7;288(23):16747-16760. doi: 10.1074/jbc.M112.438416. Epub 2013 Apr 14. J Biol Chem. 2013. PMID: 23589290 Free PMC article.
Purification of Glycosylphosphatidylinositol-Anchored Mucins from Trypanosoma cruzi Trypomastigotes and Synthesis of α-Gal-Containing Neoglycoproteins: Application as Biomarkers for Reliable Diagnosis and Early Assessment of Chemotherapeutic Outcomes of Chagas Disease.
Ortega-Rodriguez U, Portillo S, Ashmus RA, Duran JA, Schocker NS, Iniguez E, Montoya AL, Zepeda BG, Olivas JJ, Karimi NH, Alonso-Padilla J, Izquierdo L, Pinazo MJ, de Noya BA, Noya O, Maldonado RA, Torrico F, Gascon J, Michael K, Almeida IC. Ortega-Rodriguez U, et al. Among authors: maldonado ra. Methods Mol Biol. 2019;1955:287-308. doi: 10.1007/978-1-4939-9148-8_22. Methods Mol Biol. 2019. PMID: 30868536 Free PMC article.
New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 clinical trial in the Plurinational State of Bolivia.
Alonso-Vega C, Urbina JA, Sanz S, Pinazo MJ, Pinto JJ, Gonzalez VR, Rojas G, Ortiz L, Garcia W, Lozano D, Soy D, Maldonado RA, Nagarkatti R, Debrabant A, Schijman A, Thomas MC, López MC, Michael K, Ribeiro I, Gascon J, Torrico F, Almeida IC. Alonso-Vega C, et al. Among authors: maldonado ra. BMJ Open. 2021 Dec 31;11(12):e052897. doi: 10.1136/bmjopen-2021-052897. BMJ Open. 2021. PMID: 34972765 Free PMC article. Clinical Trial.
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