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Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance.
Phan T, Ribeiro RM, Edelstein GE, Boucau J, Uddin R, Marino C, Liew MY, Barry M, Choudhary MC, Tien D, Su K, Reynolds Z, Li Y, Sagar S, Vyas TD, Kawano Y, Sparks JA, Hammond SP, Wallace Z, Vyas JM, Li JZ, Siedner MJ, Barczak AK, Lemieux JE, Perelson AS. Phan T, et al. Among authors: sagar s. bioRxiv [Preprint]. 2024 Sep 16:2024.09.13.613000. doi: 10.1101/2024.09.13.613000. bioRxiv. 2024. PMID: 39345409 Free PMC article. Preprint.
SARS-CoV-2 virologic rebound with nirmatrelvir-ritonavir therapy.
Edelstein GE, Boucau J, Uddin R, Marino C, Liew MY, Barry M, Choudhary MC, Gilbert RF, Reynolds Z, Li Y, Tien D, Sagar S, Vyas TD, Kawano Y, Sparks JA, Hammond SP, Wallace Z, Vyas JM, Barczak AK, Lemieux JE, Li JZ, Siedner MJ. Edelstein GE, et al. Among authors: sagar s. medRxiv [Preprint]. 2023 Jun 27:2023.06.23.23288598. doi: 10.1101/2023.06.23.23288598. medRxiv. 2023. Update in: Ann Intern Med. 2023 Dec;176(12):1577-1585. doi: 10.7326/M23-1756 PMID: 37425934 Free PMC article. Updated. Preprint.
SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynold Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. Among authors: sagar s. medRxiv [Preprint]. 2023 Aug 7:2023.07.31.23293441. doi: 10.1101/2023.07.31.23293441. medRxiv. 2023. Update in: Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599 PMID: 37577493 Free PMC article. Updated. Preprint.
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynolds Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. Among authors: sagar s. Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266109 Free PMC article.
An acute microglial metabolic response controls metabolism and improves memory.
Drougard A, Ma EH, Wegert V, Sheldon R, Panzeri I, Vatsa N, Apostle S, Fagnocchi L, Schaf J, Gossens K, Völker J, Pang S, Bremser A, Dror E, Giacona F, Sagar S, Henderson MX, Prinz M, Jones RG, Pospisilik JA. Drougard A, et al. Among authors: sagar s. Elife. 2024 Dec 3;12:RP87120. doi: 10.7554/eLife.87120. Elife. 2024. PMID: 39625057 Free PMC article.
Evaluating a rapid molecular assay in a mobile laboratory for improved diagnosis of dengue in Bangladesh.
Hossain F, Ghosh P, Chowdhury FR, Basher A, Ahsan HMN, Khan AH, Shumu SJ, Jahan T, Roy CK, Arefin AKMN, Khanam F, Rahat MA, Chowdhury R, Uddin MR, Shomik MS, Maruf S, Rashid MU, Sagar SK, Mithila NT, Chowdhury MAA, Kamal M, Sharfaraz A, Ghosh D, Chowdhury A, Chowdhury AH, Hossain Z, Arefeen F, Islam MS, Rahman SMM, Al-Amin TM, Rashid A, Shukla KK, Roy S, Rana MS, Hossain MS, Siegel M, Wahed AAE, Mondal D. Hossain F, et al. Among authors: sagar sk. Int J Infect Dis. 2024 Nov 15;150:107299. doi: 10.1016/j.ijid.2024.107299. Online ahead of print. Int J Infect Dis. 2024. PMID: 39549784 Free article.
Relevance of intra-abdominal pressure monitoring in non-operative management of patients with blunt liver and splenic injuries.
Kumar V, Vaidyanathan R, Bagaria D, Priyadarshini P, Kumar A, Choudhary N, Sagar S, Gupta A, Mishra B, Joshi M, Soni KD, Aggarwal R, Kumar S. Kumar V, et al. Among authors: sagar s. Chin J Traumatol. 2024 Oct 30:S1008-1275(24)00152-4. doi: 10.1016/j.cjtee.2024.02.006. Online ahead of print. Chin J Traumatol. 2024. PMID: 39510959 Free article.
635 results