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Page 1
Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee SW, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies J, Gutierrez A, Kelliher M, Van Loo P, Dawson MA, Mansour MR. Rahman S, et al. Among authors: rapoz d silva t. Blood. 2024 Sep 24:blood.2024024300. doi: 10.1182/blood.2024024300. Online ahead of print. Blood. 2024. PMID: 39316719 Free article.
Molecular, clinical, and therapeutic determinants of outcome in NPM1-mutated AML.
Othman J, Potter N, Ivey A, Tazi Y, Papaemmanuil E, Jovanovic J, Freeman SD, Gilkes A, Gale R, Rapoz-D'Silva T, Runglall M, Kleeman M, Dhami P, Thomas I, Johnson S, Canham J, Cavenagh J, Kottaridis P, Arnold C, Ommen HB, Overgaard UM, Dennis M, Burnett A, Wilhelm-Benartzi C, Huntly B, Russell NH, Dillon R. Othman J, et al. Among authors: rapoz d silva t. Blood. 2024 Aug 15;144(7):714-728. doi: 10.1182/blood.2024024310. Blood. 2024. PMID: 38691678
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Maciocia PM, Wawrzyniecka PA, Maciocia NC, Burley A, Karpanasamy T, Devereaux S, Hoekx M, O'Connor D, Leon T, Rapoz-D'Silva T, Pocock R, Rahman S, Gritti G, Yánez DC, Ross S, Crompton T, Williams O, Lee L, Pule MA, Mansour MR. Maciocia PM, et al. Among authors: rapoz d silva t. Blood. 2022 Jul 7;140(1):25-37. doi: 10.1182/blood.2021013648. Blood. 2022. PMID: 35507686 Free article.
EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
León TE, Rapoz-D'Silva T, Bertoli C, Rahman S, Magnussen M, Philip B, Farah N, Richardson SE, Ahrabi S, Guerra-Assunção JA, Gupta R, Nacheva EP, Henderson S, Herrero J, Linch DC, de Bruin RAM, Mansour MR. León TE, et al. Among authors: rapoz d silva t. Cancer Discov. 2020 Jul;10(7):998-1017. doi: 10.1158/2159-8290.CD-19-0789. Epub 2020 Apr 29. Cancer Discov. 2020. PMID: 32349972 Free PMC article.