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Page 1
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.
Kumar R, Coronel L, Somalanka B, Raju A, Aning OA, An O, Ho YS, Chen S, Mak SY, Hor PY, Yang H, Lakshmanan M, Itoh H, Tan SY, Lim YK, Wong APC, Chew SH, Huynh TH, Goh BC, Lim CY, Tergaonkar V, Cheok CF. Kumar R, et al. Among authors: mak sy. Nat Commun. 2018 Sep 26;9(1):3931. doi: 10.1038/s41467-018-05805-1. Nat Commun. 2018. PMID: 30258081 Free PMC article.
Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia.
Fukawa T, Yan-Jiang BC, Min-Wen JC, Jun-Hao ET, Huang D, Qian CN, Ong P, Li Z, Chen S, Mak SY, Lim WJ, Kanayama HO, Mohan RE, Wang RR, Lai JH, Chua C, Ong HS, Tan KK, Ho YS, Tan IB, Teh BT, Shyh-Chang N. Fukawa T, et al. Among authors: mak sy. Nat Med. 2016 Jun;22(6):666-71. doi: 10.1038/nm.4093. Epub 2016 May 2. Nat Med. 2016. PMID: 27135739
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.
Penny HL, Sieow JL, Adriani G, Yeap WH, See Chi Ee P, San Luis B, Lee B, Lee T, Mak SY, Ho YS, Lam KP, Ong CK, Huang RY, Ginhoux F, Rotzschke O, Kamm RD, Wong SC. Penny HL, et al. Among authors: mak sy. Oncoimmunology. 2016 Jun 21;5(8):e1191731. doi: 10.1080/2162402X.2016.1191731. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622062 Free PMC article.
Multi-omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality.
Lee AP, Kok YJ, Lakshmanan M, Leong D, Zheng L, Lim HL, Chen S, Mak SY, Ang KS, Templeton N, Salim T, Wei X, Gifford E, Tan AH, Bi X, Ng SK, Lee DY, Ling WLW, Ho YS. Lee AP, et al. Among authors: mak sy. Biotechnol Bioeng. 2021 Nov;118(11):4305-4316. doi: 10.1002/bit.27899. Epub 2021 Jul 31. Biotechnol Bioeng. 2021. PMID: 34289087
Antibody glycan quality predicted from CHO cell culture media markers and machine learning.
Lakshmanan M, Chia S, Pang KT, Sim LC, Teo G, Mak SY, Chen S, Lim HL, Lee AP, Bin Mahfut F, Ng SK, Yang Y, Soh A, Tan AH, Choo A, Ho YS, Nguyen-Khuong T, Walsh I. Lakshmanan M, et al. Among authors: mak sy. Comput Struct Biotechnol J. 2024 Jun 1;23:2497-2506. doi: 10.1016/j.csbj.2024.05.046. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38966680 Free PMC article.
A synbiotic intervention modulates meta-omics signatures of gut redox potential and acidity in elective caesarean born infants.
Lay C, Chu CW, Purbojati RW, Acerbi E, Drautz-Moses DI, de Sessions PF, Jie S, Ho E, Kok YJ, Bi X, Chen S, Mak SY, Chua MC, Goh AEN, Chiang WC, Rao R, Chaithongwongwatthana S, Khemapech N, Chongsrisawat V, Martin R; JULIUS Study Group; Roeselers G, Ho YS, Hibberd ML, Schuster SC, Knol J. Lay C, et al. Among authors: mak sy. BMC Microbiol. 2021 Jun 25;21(1):191. doi: 10.1186/s12866-021-02230-1. BMC Microbiol. 2021. PMID: 34172012 Free PMC article. Clinical Trial.
35 results