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Page 1
Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults.
Gong Q, Sharma M, Kuan EL, Glass MC, Chander A, Singh M, Graybuck LT, Thomson ZJ, LaFrance CM, Zaim SR, Peng T, Okada LY, Genge PC, Henderson KE, Dornisch EM, Layton ED, Wittig PJ, Heubeck AT, Mukuka NM, Reading J, Roll CR, Hernandez V, Parthasarathy V, Stuckey TJ, Musgrove B, Swanson E, Lord C, Weiss MDA, Phalen CG, Mettey RR, Lee KJ, Johanneson JB, Kawelo EK, Garber J, Krishnan U, Smithmyer M, Wherry EJ, Vella L, Henrickson SE, Kopp MS, Savage AK, Becker LA, Meijer P, Coffey EM, Goronzy JJ, Speake C, Bumol TF, Goldrath AW, Torgerson TR, Li XJ, Skene PJ, Buckner JH, Gustafson CE. Gong Q, et al. Among authors: roll cr. bioRxiv [Preprint]. 2024 Sep 14:2024.09.10.612119. doi: 10.1101/2024.09.10.612119. bioRxiv. 2024. PMID: 39314416 Free PMC article. Preprint.
Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence.
Talla A, Vasaikar SV, Lemos MP, Moodie Z, Lee Pebworth MP, Henderson KE, Cohen KW, Czartoski JL, Lai L, Suthar MS, Heubeck AT, Genge PC, Roll CR, Weiss M, Reading J, Kondza N, MacMillan H, Fong OC, Thomson ZJ, Graybuck LT, Okada LY, Newell EW, Coffey EM, Meijer P, Becker LA, De Rosa SC, Skene PJ, Torgerson TR, Li XJ, Szeto GL, McElrath MJ, Bumol TF. Talla A, et al. Among authors: roll cr. bioRxiv [Preprint]. 2021 Aug 19:2021.05.26.442666. doi: 10.1101/2021.05.26.442666. bioRxiv. 2021. PMID: 34075380 Free PMC article. Preprint.
Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE. Thomson Z, et al. Among authors: roll cr. Nat Immunol. 2023 Nov;24(11):1947-1959. doi: 10.1038/s41590-023-01641-8. Epub 2023 Oct 16. Nat Immunol. 2023. PMID: 37845489 Free PMC article.
Optimized workflow for human PBMC multiomic immunosurveillance studies.
Genge PC, Roll CR, Heubeck AT, Swanson E, Kondza N, Lord C, Weiss M, Hernandez V, Phalen C, Thomson Z, Torgerson TR, Skene PJ, Bumol TF, Reading J. Genge PC, et al. Among authors: roll cr. STAR Protoc. 2021 Nov 5;2(4):100900. doi: 10.1016/j.xpro.2021.100900. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34806044 Free PMC article.
Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE. Thomson Z, et al. Among authors: roll cr. Nat Immunol. 2024 Mar;25(3):577. doi: 10.1038/s41590-024-01757-5. Nat Immunol. 2024. PMID: 38267693 Free PMC article. No abstract available.
Systemic inflammation and lymphocyte activation precede rheumatoid arthritis.
He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen K, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. He Z, et al. Among authors: roll cr. bioRxiv [Preprint]. 2024 Nov 12:2024.10.25.620344. doi: 10.1101/2024.10.25.620344. bioRxiv. 2024. PMID: 39554042 Free PMC article. Preprint.
Sterile production of interferons in the thymus affects T cell repertoire selection.
Ashby KM, Vobořil M, Salgado OC, Lee ST, Martinez RJ, O'Connor CH, Breed ER, Xuan S, Roll CR, Bachigari S, Heiland H, Stetson DB, Kotenko SV, Hogquist KA. Ashby KM, et al. Among authors: roll cr. Sci Immunol. 2024 Jul 26;9(97):eadp1139. doi: 10.1126/sciimmunol.adp1139. Epub 2024 Jul 26. Sci Immunol. 2024. PMID: 39058762