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Molecular basis of the urate transporter URAT1 inhibition by gout drugs.
Suo Y, Fedor JG, Zhang H, Tsolova K, Shi X, Sharma K, Kumari S, Borgnia M, Zhan P, Im W, Lee SY. Suo Y, et al. Among authors: borgnia m. bioRxiv [Preprint]. 2024 Sep 12:2024.09.11.612563. doi: 10.1101/2024.09.11.612563. bioRxiv. 2024. PMID: 39314352 Free PMC article. Preprint.
Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans: A target for antifungals.
Washington EJ, Zhou Y, Hsu AL, Petrovich M, Tenor JL, Toffaletti DL, Guan Z, Perfect JR, Borgnia MJ, Bartesaghi A, Brennan RG. Washington EJ, et al. Among authors: borgnia mj. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2314087121. doi: 10.1073/pnas.2314087121. Epub 2024 Jul 31. Proc Natl Acad Sci U S A. 2024. PMID: 39083421 Free PMC article.
A higher order PUF complex is central to regulation of C. elegans germline stem cells.
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Tanaka Hall TM. Qiu C, et al. Among authors: borgnia mj. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.599074. doi: 10.1101/2024.06.14.599074. bioRxiv. 2024. PMID: 38915480 Free PMC article. Preprint.
Antiviral drug recognition and elevator-type transport motions of CNT3.
Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY. Wright NJ, et al. Among authors: borgnia mj. Nat Chem Biol. 2024 Sep;20(9):1144-1153. doi: 10.1038/s41589-024-01559-8. Epub 2024 Feb 28. Nat Chem Biol. 2024. PMID: 38418906
101 results