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Symmetry of loop extrusion by dimeric SMC complexes is DNA-tension-dependent.
Pradhan B, Pinto A, Kanno T, Tetiker D, Baaske MD, Cutt E, Chatzicharlampous C, Schüler H, Deep A, Corbett KD, Aragon L, Virnau P, Björkegren C, Kim E. Pradhan B, et al. bioRxiv [Preprint]. 2024 Sep 12:2024.09.12.612694. doi: 10.1101/2024.09.12.612694. bioRxiv. 2024. PMID: 39314301 Free PMC article. Preprint.
The Smc5/6 complex is a DNA loop-extruding motor.
Pradhan B, Kanno T, Umeda Igarashi M, Loke MS, Baaske MD, Wong JSK, Jeppsson K, Björkegren C, Kim E. Pradhan B, et al. Nature. 2023 Apr;616(7958):843-848. doi: 10.1038/s41586-023-05963-3. Epub 2023 Apr 19. Nature. 2023. PMID: 37076626 Free PMC article.
Condensin-driven loop extrusion on supercoiled DNA.
Kim E, Gonzalez AM, Pradhan B, van der Torre J, Dekker C. Kim E, et al. Among authors: pradhan b. Nat Struct Mol Biol. 2022 Jul;29(7):719-727. doi: 10.1038/s41594-022-00802-x. Epub 2022 Jul 14. Nat Struct Mol Biol. 2022. PMID: 35835864
Potassium/sodium cation carriers robustly up-regulate CD20 antigen by targeting MYC, and synergize with anti-CD20 immunotherapies to eliminate malignant B cells.
Torun A, Zdanowicz A, Miazek-Zapala N, Zapala P, Pradhan B, Jedrzejczyk M, Ciechanowicz A, Pilch Z, Skorzynski M, Słabicki M, Rymkiewicz G, Barankiewicz J, Martines C, Laurenti L, Struga M, Winiarska M, Golab J, Kucia M, Ratajczak MZ, Huczynski A, Calado DP, Efremov DG, Zerrouqi A, Pyrzynska B. Torun A, et al. Among authors: pradhan b. Haematologica. 2024 Dec 19. doi: 10.3324/haematol.2024.285826. Online ahead of print. Haematologica. 2024. PMID: 39704178 Free article.
483 results