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Novel Pannexin 1 isoform is increased in cancer.
O'Donnell BL, Stefan D, Chiu YH, Zeitz MJ, Tang J, Johnston D, Leighton SE, Kessel CV, Barr K, Gyenis L, Freeman TJ, Kelly JJ, Sayedyahossein S, Litchfield DW, Roth K, Smyth JW, Hebb M, Ronald J, Bayliss DA, Penuela S. O'Donnell BL, et al. Among authors: litchfield dw. bioRxiv [Preprint]. 2024 Sep 11:2024.09.09.612143. doi: 10.1101/2024.09.09.612143. bioRxiv. 2024. PMID: 39314291 Free PMC article. Preprint.
Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells.
Hermosilla VE, Gyenis L, Rabalski AJ, Armijo ME, Sepúlveda P, Duprat F, Benítez-Riquelme D, Fuentes-Villalobos F, Quiroz A, Hepp MI, Farkas C, Mastel M, González-Chavarría I, Jackstadt R, Litchfield DW, Castro AF, Pincheira R. Hermosilla VE, et al. Among authors: litchfield dw. Cell Death Dis. 2024 Mar 16;15(3):223. doi: 10.1038/s41419-024-06591-z. Cell Death Dis. 2024. PMID: 38493149 Free PMC article.
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B. Reinecke M, et al. Among authors: litchfield dw. Nat Chem Biol. 2024 May;20(5):577-585. doi: 10.1038/s41589-023-01459-3. Epub 2023 Oct 30. Nat Chem Biol. 2024. PMID: 37904048 Free PMC article.
Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics.
Gyenis L, Menyhart D, Cruise ES, Jurcic K, Roffey SE, Chai DB, Trifoi F, Fess SR, Desormeaux PJ, Núñez de Villavicencio Díaz T, Rabalski AJ, Zukowski SA, Turowec JP, Pittock P, Lajoie G, Litchfield DW. Gyenis L, et al. Among authors: litchfield dw. Front Mol Biosci. 2022 Jun 9;9:909711. doi: 10.3389/fmolb.2022.909711. eCollection 2022. Front Mol Biosci. 2022. PMID: 35755813 Free PMC article.
CSNK2 in cancer: pathophysiology and translational applications.
Strum SW, Gyenis L, Litchfield DW. Strum SW, et al. Among authors: litchfield dw. Br J Cancer. 2022 Apr;126(7):994-1003. doi: 10.1038/s41416-021-01616-2. Epub 2021 Nov 12. Br J Cancer. 2022. PMID: 34773100 Free PMC article. Review.
CK2 Regulation: Perspectives in 2021.
Roffey SE, Litchfield DW. Roffey SE, et al. Among authors: litchfield dw. Biomedicines. 2021 Sep 30;9(10):1361. doi: 10.3390/biomedicines9101361. Biomedicines. 2021. PMID: 34680478 Free PMC article. Review.
132 results