Samarasinghe KTG - Search Results

1

Protein phosphatase PP2Cα S-glutathionylation regulates cell migration.

Kukulage DSK, Samarasinghe KTG, Matarage Don NNJ, Shivamadhu MC, Shishikura K, Schiff W, Mashhadi Ramezani F, Padmavathi R, Matthews ML, Ahn YH. Kukulage DSK, et al. Among authors: samarasinghe ktg. J Biol Chem. 2024 Oct;300(10):107784. doi: 10.1016/j.jbc.2024.107784. Epub 2024 Sep 18. J Biol Chem. 2024. PMID: 39303918 Free PMC article.

2

Clickable glutathione using tetrazine-alkene bioorthogonal chemistry for detecting protein glutathionylation.

Kekulandara DN, Samarasinghe KT, Munkanatta Godage DN, Ahn YH. Kekulandara DN, et al. Org Biomol Chem. 2016 Nov 22;14(46):10886-10893. doi: 10.1039/c6ob02050j. Org Biomol Chem. 2016. PMID: 27812596

3

Correction: Clickable glutathione using tetrazine-alkene bioorthogonal chemistry for detecting protein glutathionylation.

Kekulandara DN, Samarasinghe KTG, Munkanatta Godage DNP, Ahn YH. Kekulandara DN, et al. Among authors: samarasinghe ktg. Org Biomol Chem. 2018 Apr 4;16(14):2576. doi: 10.1039/c8ob90044b. Org Biomol Chem. 2018. PMID: 29617025

4

Metabolic synthesis of clickable glutathione for chemoselective detection of glutathionylation.

Samarasinghe KT, Munkanatta Godage DN, VanHecke GC, Ahn YH. Samarasinghe KT, et al. J Am Chem Soc. 2014 Aug 20;136(33):11566-9. doi: 10.1021/ja503946q. Epub 2014 Aug 11. J Am Chem Soc. 2014. PMID: 25079194

5

A clickable glutathione approach for identification of protein glutathionylation in response to glucose metabolism.

Samarasinghe KT, Munkanatta Godage DN, Zhou Y, Ndombera FT, Weerapana E, Ahn YH. Samarasinghe KT, et al. Mol Biosyst. 2016 Jul 19;12(8):2471-80. doi: 10.1039/c6mb00175k. Mol Biosyst. 2016. PMID: 27216279 Free PMC article.

6

Identification and Quantification of Glutathionylated Cysteines under Ischemic Stress.

Yapa Abeywardana M, Samarasinghe KTG, Munkanatta Godage D, Ahn YH. Yapa Abeywardana M, et al. Among authors: samarasinghe ktg. J Proteome Res. 2021 Sep 3;20(9):4529-4542. doi: 10.1021/acs.jproteome.1c00473. Epub 2021 Aug 12. J Proteome Res. 2021. PMID: 34382403 Free PMC article.

7

SMYD2 glutathionylation contributes to degradation of sarcomeric proteins.

Munkanatta Godage DNP, VanHecke GC, Samarasinghe KTG, Feng HZ, Hiske M, Holcomb J, Yang Z, Jin JP, Chung CS, Ahn YH. Munkanatta Godage DNP, et al. Among authors: samarasinghe ktg. Nat Commun. 2018 Oct 18;9(1):4341. doi: 10.1038/s41467-018-06786-x. Nat Commun. 2018. PMID: 30337525 Free PMC article.

8

Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras.

Samarasinghe KTG, Jaime-Figueroa S, Burgess M, Nalawansha DA, Dai K, Hu Z, Bebenek A, Holley SA, Crews CM. Samarasinghe KTG, et al. Cell Chem Biol. 2021 May 20;28(5):648-661.e5. doi: 10.1016/j.chembiol.2021.03.011. Epub 2021 Apr 8. Cell Chem Biol. 2021. PMID: 33836141 Free PMC article.

9

Targeted protein degradation: A promise for undruggable proteins.

Samarasinghe KTG, Crews CM. Samarasinghe KTG, et al. Cell Chem Biol. 2021 Jul 15;28(7):934-951. doi: 10.1016/j.chembiol.2021.04.011. Epub 2021 May 17. Cell Chem Biol. 2021. PMID: 34004187 Free PMC article. Review.

10

OligoTRAFTACs: A generalizable method for transcription factor degradation.

Samarasinghe KTG, An E, Genuth MA, Chu L, Holley SA, Crews CM. Samarasinghe KTG, et al. RSC Chem Biol. 2022 Jul 26;3(9):1144-1153. doi: 10.1039/d2cb00138a. eCollection 2022 Aug 31. RSC Chem Biol. 2022. PMID: 36128504 Free PMC article.

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