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Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation.
Gosztyla ML, Zhan L, Olson S, Wei X, Naritomi J, Nguyen G, Street L, Goda GA, Cavazos FF, Schmok JC, Jain M, Uddin Syed E, Kwon E, Jin W, Kofman E, Tankka AT, Li A, Gonzalez V, Lécuyer E, Dominguez D, Jovanovic M, Graveley BR, Yeo GW. Gosztyla ML, et al. Among authors: kofman e. Mol Cell. 2024 Oct 3;84(19):3826-3842.e8. doi: 10.1016/j.molcel.2024.08.010. Epub 2024 Sep 19. Mol Cell. 2024. PMID: 39303722 Free article.
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.
Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. Xiang JS, et al. Among authors: kofman er. bioRxiv [Preprint]. 2022 Feb 23:2022.02.21.481223. doi: 10.1101/2022.02.21.481223. bioRxiv. 2022. PMID: 35233578 Free PMC article. Preprint.
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.
Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Croker BA, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Clark AE, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. Xiang JS, et al. Among authors: kofman er. Res Sq [Preprint]. 2022 Mar 17:rs.3.rs-1394331. doi: 10.21203/rs.3.rs-1394331/v1. Res Sq. 2022. PMID: 35313591 Free PMC article. Preprint.
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies.
Medina-Munoz HC, Kofman E, Jagannatha P, Boyle EA, Yu T, Jones KL, Mueller JR, Lykins GD, Doudna AT, Park SS, Blue SM, Ranzau BL, Kohli RM, Komor AC, Yeo GW. Medina-Munoz HC, et al. Among authors: kofman e. Nat Commun. 2024 Jan 29;15(1):875. doi: 10.1038/s41467-024-45009-4. Nat Commun. 2024. PMID: 38287010 Free PMC article.
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies.
Medina-Munoz HC, Kofman E, Jagannatha P, Boyle EA, Yu T, Jones KL, Mueller JR, Lykins GD, Doudna AT, Park SS, Blue SM, Ranzau BL, Kohli RM, Komor AC, Yeo GW. Medina-Munoz HC, et al. Among authors: kofman e. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558915. doi: 10.1101/2023.09.25.558915. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 29;15(1):875. doi: 10.1038/s41467-024-45009-4. PMID: 37808757 Free PMC article. Updated. Preprint.
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation.
Abe Y, Kofman ER, Ouyang Z, Cruz-Becerra G, Spann NJ, Seidman JS, Troutman TD, Stender JD, Taylor H, Fan W, Link VM, Shen Z, Sakai J, Downes M, Evans RM, Kadonaga JT, Rosenfeld MG, Glass CK. Abe Y, et al. Among authors: kofman er. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2316104121. doi: 10.1073/pnas.2316104121. Epub 2024 Jan 2. Proc Natl Acad Sci U S A. 2024. PMID: 38165941 Free PMC article.
Discovery and Evaluation of TLR-Targeted Immune Agonists.
Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, Kofman E, Raoufi F, Dang X, Bao J, Tomazela D, Baily M, Geierstanger B, Flygare JA, Han JH, Willingham A, Seganish WM. Chernyak N, et al. Among authors: kofman e. J Med Chem. 2024 Sep 26;67(18):16222-16234. doi: 10.1021/acs.jmedchem.4c00804. Epub 2024 Sep 5. J Med Chem. 2024. PMID: 39235949
Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.
Patel AM, Willingham A, Cheng AC, Tomazela D, Bowman E, Kofman E, Zhang F, Bao J, Sanzone JR, Choy JW, Flygare JA, Han JH, Pradhan K, Kieffer M, Chernyak N, Akbari P, Liu P, Mehmood R, Naravula S, Hollingsworth SA, Bhagwat B, Lang SB, Seganish WM. Patel AM, et al. Among authors: kofman e. J Med Chem. 2024 Sep 12;67(17):15756-15779. doi: 10.1021/acs.jmedchem.4c01384. Epub 2024 Aug 22. J Med Chem. 2024. PMID: 39172064
75 results