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Triple-targeted therapy of dabrafenib, trametinib, and osimertinib for the treatment of the acquired BRAF V600E mutation after progression on EGFR-tyrosine kinase inhibitors in advanced EGFR-mutated non-small cell lung cancer patients.
Weng CD, Liu KJ, Jin S, Su JW, Yao YH, Zhou CZ, Li YF, Chen ZX, Chen HJ, Li YY, Tang KJ, Yang JJ. Weng CD, et al. Among authors: chen hj. Transl Lung Cancer Res. 2024 Oct 31;13(10):2538-2548. doi: 10.21037/tlcr-24-358. Epub 2024 Oct 28. Transl Lung Cancer Res. 2024. PMID: 39507030 Free PMC article.
Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation.
Craven GB, Chu H, Sun JD, Carelli JD, Coyne B, Chen H, Chen Y, Ma X, Das S, Kong W, Zajdlik AD, Yang KS, Reisberg SH, Thompson PA, Lipford JR, Taunton J. Craven GB, et al. Among authors: chen h. Nature. 2024 Nov 6. doi: 10.1038/s41586-024-08176-4. Online ahead of print. Nature. 2024. PMID: 39506119
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