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Association of MTHFR C677T, MTHFRA1298C and MTRRA66G gene polymorphisms with hyperhomocysteinemia and its modulation by the combined effect of vitamin B12 and folate in a hypertensive Chinese population.
Siddiqi SM, Liu L, Du Y, Song Y, Chen P, Li S, He Q, Zhou Z, Xu J, Bai J, Wang B, Qin X, Mehmood A, Xiuqing L, Cheng X, Shi HP. Siddiqi SM, et al. J Nutr. 2024 Sep 17:S0022-3166(24)01014-9. doi: 10.1016/j.tjnut.2024.09.003. Online ahead of print. J Nutr. 2024. PMID: 39299473

RESULTS: Our findings revealed significant sex differences in tHcy levels, with males exhibiting higher tHcy levels than females (13.95 mumol/L vs. 11.15 mumol/L, p < 0.001). Individuals deficient in both vitamin B12 and folate had an increased risk of H-Hcy (57.

RESULTS: Our findings revealed significant sex differences in tHcy levels, with males exhibiting higher tHcy levels than females (13.95 mumo …