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High-resolution functional mapping of RAD51C by saturation genome editing.
Olvera-León R, Zhang F, Offord V, Zhao Y, Tan HK, Gupta P, Pal T, Robles-Espinoza CD, Arriaga-González FG, Matsuyama LSAS, Delage E, Dicks E, Ezquina S, Rowlands CF, Turnbull C, Pharoah P, Perry JRB, Jasin M, Waters AJ, Adams DJ. Olvera-León R, et al. Among authors: jasin m. Cell. 2024 Sep 16:S0092-8674(24)00968-1. doi: 10.1016/j.cell.2024.08.039. Online ahead of print. Cell. 2024. PMID: 39299233
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin.
Carver A, Yu TY, Yates LA, White T, Wang R, Lister K, Jasin M, Zhang X. Carver A, et al. Among authors: jasin m. bioRxiv [Preprint]. 2024 Jul 16:2024.07.16.603765. doi: 10.1101/2024.07.16.603765. bioRxiv. 2024. PMID: 39071279 Free PMC article. Preprint.
In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis.
Matos-Rodrigues G, Barroca V, Muhammad AA, Dardillac E, Allouch A, Koundrioukoff S, Lewandowski D, Despras E, Guirouilh-Barbat J, Frappart L, Kannouche P, Dupaigne P, Le Cam E, Perfettini JL, Romeo PH, Debatisse M, Jasin M, Livera G, Martini E, Lopez BS. Matos-Rodrigues G, et al. Among authors: jasin m. EMBO J. 2023 Oct 16;42(20):e110844. doi: 10.15252/embj.2022110844. Epub 2023 Sep 4. EMBO J. 2023. PMID: 37661798 Free PMC article.
Structural insights into BCDX2 complex function in homologous recombination.
Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK. Rawal Y, et al. Among authors: jasin m. Nature. 2023 Jul;619(7970):640-649. doi: 10.1038/s41586-023-06219-w. Epub 2023 Jun 21. Nature. 2023. PMID: 37344589 Free PMC article.
Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants.
Prakash R, Rawal Y, Sullivan MR, Grundy MK, Bret H, Mihalevic MJ, Rein HL, Baird JM, Darrah K, Zhang F, Wang R, Traina TA, Radke MR, Kaufmann SH, Swisher EM, Guérois R, Modesti M, Sung P, Jasin M, Bernstein KA. Prakash R, et al. Among authors: jasin m. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2202727119. doi: 10.1073/pnas.2202727119. Epub 2022 Sep 13. Proc Natl Acad Sci U S A. 2022. PMID: 36099300 Free PMC article.
242 results