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Targeting cancer with small-molecule pan-KRAS degraders.
Science. 2024 Sep 20;385(6715):1338-1347. doi: 10.1126/science.adm8684. Epub 2024 Sep 19.
Science. 2024.
PMID: 39298590
Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.
Farnaby W, et al. Among authors: zollman d.
Nat Chem Biol. 2019 Aug;15(8):846. doi: 10.1038/s41589-019-0329-z.
Nat Chem Biol. 2019.
PMID: 31267096
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BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.
Farnaby W, et al. Among authors: zollman d.
Nat Chem Biol. 2019 Jul;15(7):672-680. doi: 10.1038/s41589-019-0294-6. Epub 2019 Jun 10.
Nat Chem Biol. 2019.
PMID: 31178587
Free PMC article.
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In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.
Cain R, Brem J, Zollman D, McDonough MA, Johnson RM, Spencer J, Makena A, Abboud MI, Cahill S, Lee SY, McHugh PJ, Schofield CJ, Fishwick CWG.
Cain R, et al. Among authors: zollman d.
J Med Chem. 2018 Feb 8;61(3):1255-1260. doi: 10.1021/acs.jmedchem.7b01728. Epub 2018 Jan 10.
J Med Chem. 2018.
PMID: 29271657
Free article.
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Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers.
Brem J, van Berkel SS, Zollman D, Lee SY, Gileadi O, McHugh PJ, Walsh TR, McDonough MA, Schofield CJ.
Brem J, et al. Among authors: zollman d.
Antimicrob Agents Chemother. 2015 Oct 19;60(1):142-50. doi: 10.1128/AAC.01335-15. Print 2016 Jan.
Antimicrob Agents Chemother. 2015.
PMID: 26482303
Free PMC article.
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The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction.
Koehnke J, Bent AF, Zollman D, Smith K, Houssen WE, Zhu X, Mann G, Lebl T, Scharff R, Shirran S, Botting CH, Jaspars M, Schwarz-Linek U, Naismith JH.
Koehnke J, et al. Among authors: zollman d.
Angew Chem Int Ed Engl. 2013 Dec 23;52(52):13991-6. doi: 10.1002/anie.201306302. Epub 2013 Nov 8.
Angew Chem Int Ed Engl. 2013.
PMID: 24214017
Free PMC article.
No abstract available.
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The discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamides.
Houssen WE, Koehnke J, Zollman D, Vendome J, Raab A, Smith MC, Naismith JH, Jaspars M.
Houssen WE, et al. Among authors: zollman d.
Chembiochem. 2012 Dec 21;13(18):2683-9. doi: 10.1002/cbic.201200661. Epub 2012 Nov 21.
Chembiochem. 2012.
PMID: 23169461
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The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain.
Koehnke J, Bent A, Houssen WE, Zollman D, Morawitz F, Shirran S, Vendome J, Nneoyiegbe AF, Trembleau L, Botting CH, Smith MC, Jaspars M, Naismith JH.
Koehnke J, et al. Among authors: zollman d.
Nat Struct Mol Biol. 2012 Aug;19(8):767-72. doi: 10.1038/nsmb.2340. Epub 2012 Jul 15.
Nat Struct Mol Biol. 2012.
PMID: 22796963
Free PMC article.
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