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Page 1
Targeting cancer with small-molecule pan-KRAS degraders.
Popow J, Farnaby W, Gollner A, Kofink C, Fischer G, Wurm M, Zollman D, Wijaya A, Mischerikow N, Hasenoehrl C, Prokofeva P, Arnhof H, Arce-Solano S, Bell S, Boeck G, Diers E, Frost AB, Goodwin-Tindall J, Karolyi-Oezguer J, Khan S, Klawatsch T, Koegl M, Kousek R, Kratochvil B, Kropatsch K, Lauber AA, McLennan R, Olt S, Peter D, Petermann O, Roessler V, Stolt-Bergner P, Strack P, Strauss E, Trainor N, Vetma V, Whitworth C, Zhong S, Quant J, Weinstabl H, Kuster B, Ettmayer P, Ciulli A. Popow J, et al. Among authors: strack p. Science. 2024 Sep 20;385(6715):1338-1347. doi: 10.1126/science.adm8684. Epub 2024 Sep 19. Science. 2024. PMID: 39298590
Characteristics and Outcomes of Children and Young Adults With Sepsis Requiring Continuous Renal Replacement Therapy: A Comparative Analysis From the Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK).
Stanski NL, Gist KM, Hasson D, Stenson EK, Seo J, Ollberding NJ, Muff-Luett M, Cortina G, Alobaidi R, See E, Kaddourah A, Fuhrman DY; Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Investigators. Stanski NL, et al. Crit Care Med. 2024 Sep 11. doi: 10.1097/CCM.0000000000006405. Online ahead of print. Crit Care Med. 2024. PMID: 39258974
Characteristics and outcomes of children ≤ 10 kg receiving continuous kidney replacement therapy: a WE-ROCK study.
Menon S, Starr MC, Zang H, Collins M, Damian MA, Fuhrman D, Krallman K, Soranno DE, Webb TN, Slagle C, Joseph C, Martin SD, Mohamed T, Beebe ME, Ricci Z, Ollberding N, Selewski D, Gist KM; WE-ROCK investigators. Menon S, et al. Pediatr Nephrol. 2024 Aug 20. doi: 10.1007/s00467-024-06438-x. Online ahead of print. Pediatr Nephrol. 2024. PMID: 39164502
Testing the drift-diffusion model.
Fudenberg D, Newey W, Strack P, Strzalecki T. Fudenberg D, et al. Among authors: strack p. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33141-33148. doi: 10.1073/pnas.2011446117. Epub 2020 Dec 11. Proc Natl Acad Sci U S A. 2020. PMID: 33310903 Free PMC article.
Chorismatases - the family is growing.
Grüninger MJ , Buchholz PCF , Mordhorst S , Strack P , Müller M , Hubrich F , Pleiss J , Andexer JN . Grüninger MJ , et al. Among authors: strack p. Org Biomol Chem. 2019 Feb 20;17(8):2092-2098. doi: 10.1039/c8ob03038c. Org Biomol Chem. 2019. PMID: 30706936
Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN. Severyn B, et al. Among authors: strack p. J Biomol Screen. 2016 Oct;21(9):989-97. doi: 10.1177/1087057116658646. Epub 2016 Jul 26. J Biomol Screen. 2016. PMID: 27461835
An accessible pharmacodynamic transcriptional biomarker for notch target engagement.
Tanis KQ, Podtelezhnikov AA, Blackman SC, Hing J, Railkar RA, Lunceford J, Klappenbach JA, Wei B, Harman A, Camargo LM, Shah S, Finney EM, Hardwick JS, Loboda A, Watters J, Bergstrom DA, Demuth T, Herman GA, Strack PR, Iannone R. Tanis KQ, et al. Among authors: strack pr. Clin Pharmacol Ther. 2016 Apr;99(4):370-80. doi: 10.1002/cpt.335. Epub 2016 Feb 17. Clin Pharmacol Ther. 2016. PMID: 26765077 Clinical Trial.
52 results