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Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.
Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA. Doan KV, et al. Among authors: lee wd. Nat Cardiovasc Res. 2024 Oct;3(10):1236-1248. doi: 10.1038/s44161-024-00542-9. Epub 2024 Sep 18. Nat Cardiovasc Res. 2024. PMID: 39294272
Circulating metabolite homeostasis achieved through mass action.
Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG, Lee WD, Zeng X, Jang C, Rabinowitz JD. Li X, et al. Among authors: lee wd. Nat Metab. 2022 Jan;4(1):141-152. doi: 10.1038/s42255-021-00517-1. Epub 2022 Jan 20. Nat Metab. 2022. PMID: 35058631 Free PMC article.
Slow TCA flux and ATP production in primary solid tumours but not metastases.
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD. Bartman CR, et al. Among authors: lee wd. Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1. Nature. 2023. PMID: 36725930 Free PMC article.
Impact of acute stress on murine metabolomics and metabolic flux.
Lee WD, Liang L, AbuSalim J, Jankowski CSR, Samarah LZ, Neinast MD, Rabinowitz JD. Lee WD, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2301215120. doi: 10.1073/pnas.2301215120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186827 Free PMC article.
Selected Ion Monitoring for Orbitrap-Based Metabolomics.
Lu W, McBride MJ, Lee WD, Xing X, Xu X, Li X, Oschmann AM, Shen Y, Bartman C, Rabinowitz JD. Lu W, et al. Among authors: lee wd. Metabolites. 2024 Mar 25;14(4):184. doi: 10.3390/metabo14040184. Metabolites. 2024. PMID: 38668312 Free PMC article.
Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma.
Zhang X, Lee WD, Leitner BP, Zhu W, Fosam A, Li Z, Gaspar RC, Halberstam AA, Robles B, Rabinowitz JD, Perry RJ. Zhang X, et al. Among authors: lee wd. Am J Physiol Endocrinol Metab. 2023 Oct 1;325(4):E363-E375. doi: 10.1152/ajpendo.00105.2023. Epub 2023 Aug 30. Am J Physiol Endocrinol Metab. 2023. PMID: 37646579 Free PMC article.
160 results