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Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin BK, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. Chardon FM, et al. Among authors: mcdiarmid ta. Nat Commun. 2024 Sep 18;15(1):8209. doi: 10.1038/s41467-024-52490-4. Nat Commun. 2024. PMID: 39294132 Free PMC article.
Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid TA, Daza RM, Kim H, Lalanne JB, Nathans JF, Lee DS, Shendure J. Li X, et al. Among authors: mcdiarmid ta. Cell. 2024 May 9;187(10):2411-2427.e25. doi: 10.1016/j.cell.2024.03.020. Epub 2024 Apr 11. Cell. 2024. PMID: 38608704 Free article.
Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.
Ho CH, Dippel MA, McQuade MS, Mishra A, Pribitzer S, Nguyen LP, Hardy S, Chandok H, Chardon F, McDiarmid TA, DeBerg HA, Buckner JH, Shendure J, de Boer CG, Guo MH, Tewhey R, Ray JP. Ho CH, et al. Among authors: mcdiarmid ta. bioRxiv [Preprint]. 2024 Oct 11:2024.10.07.617092. doi: 10.1101/2024.10.07.617092. bioRxiv. 2024. PMID: 39416200 Free PMC article. Preprint.
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin B, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. Chardon FM, et al. Among authors: mcdiarmid ta. bioRxiv [Preprint]. 2024 Apr 30:2023.03.28.534017. doi: 10.1101/2023.03.28.534017. bioRxiv. 2024. Update in: Nat Commun. 2024 Sep 18;15(1):8209. doi: 10.1038/s41467-024-52490-4. PMID: 37034704 Free PMC article. Updated. Preprint.
Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K. Post KL, et al. Among authors: mcdiarmid ta. Nat Commun. 2020 Apr 29;11(1):2073. doi: 10.1038/s41467-020-15943-0. Nat Commun. 2020. PMID: 32350270 Free PMC article.
18 results