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Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Widjaja AA, Lim WW, Viswanathan S, Chothani S, Corden B, Dasan CM, Goh JWT, Lim R, Singh BK, Tan J, Pua CJ, Lim SY, Adami E, Schafer S, George BL, Sweeney M, Xie C, Tripathi M, Sims NA, Hübner N, Petretto E, Withers DJ, Ho L, Gil J, Carling D, Cook SA. Widjaja AA, et al. Among authors: petretto e. Nature. 2024 Aug;632(8023):157-165. doi: 10.1038/s41586-024-07701-9. Epub 2024 Jul 17. Nature. 2024. PMID: 39020175 Free PMC article.
Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity.
Hateley C, Olona A, Halliday L, Edin ML, Ko JH, Forlano R, Terra X, Lih FB, Beltrán-Debón R, Manousou P, Purkayastha S, Moorthy K, Thursz MR, Zhang G, Goldin RD, Zeldin DC, Petretto E, Behmoaras J. Hateley C, et al. Among authors: petretto e. EBioMedicine. 2024 May;103:105127. doi: 10.1016/j.ebiom.2024.105127. Epub 2024 Apr 26. EBioMedicine. 2024. PMID: 38677183 Free PMC article.
161 results