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749 results

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Page 1
Identification of isoquinolinone DHODH inhibitor isosteres.
DeRatt LG, Zhang Z, Pietsch EC, Cisar J, Wang A, Wang CY, Tanner A, Shaffer P, Jacoby E, Kazmi F, Shukla N, Philippar U, Attar RM, Edwards JP, Kuduk SD. DeRatt LG, et al. Among authors: shukla n. Bioorg Med Chem Lett. 2024 Sep 14:129965. doi: 10.1016/j.bmcl.2024.129965. Online ahead of print. Bioorg Med Chem Lett. 2024. PMID: 39284456
Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML.
DeRatt LG, Zhang Z, Pietsch C, Cisar JS, Zhang X, Wang W, Tanner A, Matico R, Shaffer P, Jacoby E, Kazmi F, Shukla N, Bush TL, Patrick A, Philippar U, Attar R, Edwards JP, Kuduk SD. DeRatt LG, et al. Among authors: shukla n. J Med Chem. 2024 Jul 11;67(13):11254-11272. doi: 10.1021/acs.jmedchem.4c00809. Epub 2024 Jun 18. J Med Chem. 2024. PMID: 38889244
Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors.
Hickman RA, Miller AM, Holle BM, Jee J, Liu SY, Ross D, Yu H, Riely GJ, Ombres C, Gewirtz AN, Reiner AS, Nandakumar S, Price A, Kaley TJ, Graham MS, Vanderbilt C, Rana S, Hill K, Chabot K, Campos C, Nafa K, Shukla N, Karajannis M, Li B, Berger M, Ladanyi M, Pentsova E, Boire A, Brannon AR, Bale T, Mellinghoff IK, Arcila ME. Hickman RA, et al. Among authors: shukla n. Acta Neuropathol Commun. 2024 Sep 17;12(1):151. doi: 10.1186/s40478-024-01846-4. Acta Neuropathol Commun. 2024. PMID: 39289779 Free PMC article.
Induction of Endoscopic Response, Remission, and Ulcer-Free Endoscopy With Upadacitinib Is Associated With Improved Clinical Outcomes and Quality of Life in Patients With Crohn's Disease.
Panés J, Louis E, Bossuyt P, Joshi N, Lee WJ, Lacerda AP, Kligys K, Xuan S, Shukla N, Loftus EV Jr. Panés J, et al. Among authors: shukla n. Inflamm Bowel Dis. 2024 Sep 4:izae200. doi: 10.1093/ibd/izae200. Online ahead of print. Inflamm Bowel Dis. 2024. PMID: 39231444
Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community.
Cuglievan B, Kantarjian H, Rubnitz JE, Cooper TM, Zwaan CM, Pollard JA, DiNardo CD, Kadia TM, Guest E, Short NJ, McCall D, Daver N, Nunez C, Haddad FG, Garcia M, Bhalla KN, Maiti A, Catueno S, Fiskus W, Carter BZ, Gibson A, Roth M, Khazal S, Tewari P, Abbas HA, Bourgeois W, Andreeff M, Shukla NN, Truong DD, Connors J, Ludwig JA, Stutterheim J, Salzer E, Juul-Dam KL, Sasaki K, Mahadeo KM, Tasian SK, Borthakur G, Dickson S, Jain N, Jabbour E, Meshinchi S, Garcia-Manero G, Ravandi F, Stein EM, Kolb EA, Issa GC. Cuglievan B, et al. Among authors: shukla nn. Leukemia. 2024 Aug 23. doi: 10.1038/s41375-024-02368-7. Online ahead of print. Leukemia. 2024. PMID: 39179671 Review.
Daratumumab in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: DELPHINUS Study.
Bhatla T, Hogan L MD, Teachey DT, Bautista F, Moppett JP, Velasco P, Micalizzi C, Rossig C, Shukla NN, Gilad G, Locatelli F, Baruchel A, Zwaan M, Bezler NS, Rubio-San-Simón A, Taussig D, Raetz EA, Mao ZJ, Wood B, Alvarez Arias D Dr, Krevvata M, Nnane I, Bandyopadhyay N, Lopez Solano L, Dennis RM, Carson R, Vora A. Bhatla T, et al. Among authors: shukla nn. Blood. 2024 Aug 16:blood.2024024493. doi: 10.1182/blood.2024024493. Online ahead of print. Blood. 2024. PMID: 39158071
749 results