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Page 1
Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors.
Camarda ND, Lu Q, Meola DM, Man JJ, Song Z, Travers RJ, Lopez KE, Powers SN, Papanastasiou M, DeRuff KC, Mullahoo J, Egri SB, Davison D, Sebastiani P, Eblen ST, Buchsbaum R, Huggins GS, London CA, Jaffe JD, Upshaw JN, Yang VK, Jaffe IZ. Camarda ND, et al. Among authors: mullahoo j. Clin Sci (Lond). 2024 Sep 18;138(18):1131-1150. doi: 10.1042/CS20240537. Clin Sci (Lond). 2024. PMID: 39282930
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.
Gross SM, Dane MA, Smith RL, Devlin KL, McLean IC, Derrick DS, Mills CE, Subramanian K, London AB, Torre D, Evangelista JE, Clarke DJB, Xie Z, Erdem C, Lyons N, Natoli T, Pessa S, Lu X, Mullahoo J, Li J, Adam M, Wassie B, Liu M, Kilburn DF, Liby TA, Bucher E, Sanchez-Aguila C, Daily K, Omberg L, Wang Y, Jacobson C, Yapp C, Chung M, Vidovic D, Lu Y, Schurer S, Lee A, Pillai A, Subramanian A, Papanastasiou M, Fraenkel E, Feiler HS, Mills GB, Jaffe JD, Ma'ayan A, Birtwistle MR, Sorger PK, Korkola JE, Gray JW, Heiser LM. Gross SM, et al. Among authors: mullahoo j. Commun Biol. 2022 Oct 7;5(1):1066. doi: 10.1038/s42003-022-03975-9. Commun Biol. 2022. PMID: 36207580 Free PMC article.
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors.
Meharena HS, Marco A, Dileep V, Lockshin ER, Akatsu GY, Mullahoo J, Watson LA, Ko T, Guerin LN, Abdurrob F, Rengarajan S, Papanastasiou M, Jaffe JD, Tsai LH. Meharena HS, et al. Among authors: mullahoo j. Cell Stem Cell. 2022 Jan 6;29(1):116-130.e7. doi: 10.1016/j.stem.2021.12.002. Cell Stem Cell. 2022. PMID: 34995493 Free PMC article.
Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds.
Dele-Oni DO, Christianson KE, Egri SB, Vaca Jacome AS, DeRuff KC, Mullahoo J, Sharma V, Davison D, Ko T, Bula M, Blanchard J, Young JZ, Litichevskiy L, Lu X, Lam D, Asiedu JK, Toder C, Officer A, Peckner R, MacCoss MJ, Tsai LH, Carr SA, Papanastasiou M, Jaffe JD. Dele-Oni DO, et al. Among authors: mullahoo j. Sci Data. 2021 Aug 25;8(1):226. doi: 10.1038/s41597-021-01008-4. Sci Data. 2021. PMID: 34433823 Free PMC article.
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Garvie CW, Wu X, Papanastasiou M, Lee S, Fuller J, Schnitzler GR, Horner SW, Baker A, Zhang T, Mullahoo JP, Westlake L, Hoyt SH, Toetzl M, Ranaghan MJ, de Waal L, McGaunn J, Kaplan B, Piccioni F, Yang X, Lange M, Tersteegen A, Raymond D, Lewis TA, Carr SA, Cherniack AD, Lemke CT, Meyerson M, Greulich H. Garvie CW, et al. Among authors: mullahoo jp. Nat Commun. 2021 Jul 16;12(1):4375. doi: 10.1038/s41467-021-24495-w. Nat Commun. 2021. PMID: 34272366 Free PMC article.
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis.
Rossmann MP, Hoi K, Chan V, Abraham BJ, Yang S, Mullahoo J, Papanastasiou M, Wang Y, Elia I, Perlin JR, Hagedorn EJ, Hetzel S, Weigert R, Vyas S, Nag PP, Sullivan LB, Warren CR, Dorjsuren B, Greig EC, Adatto I, Cowan CA, Schreiber SL, Young RA, Meissner A, Haigis MC, Hekimi S, Carr SA, Zon LI. Rossmann MP, et al. Among authors: mullahoo j. Science. 2021 May 14;372(6543):716-721. doi: 10.1126/science.aaz2740. Science. 2021. PMID: 33986176 Free PMC article.
Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS.
Papanastasiou M, Mullahoo J, DeRuff KC, Bajrami B, Karageorgos I, Johnston SE, Peckner R, Myers SA, Carr SA, Jaffe JD. Papanastasiou M, et al. Among authors: mullahoo j. Mol Cell Proteomics. 2019 Oct;18(10):2089-2098. doi: 10.1074/mcp.RA119.001325. Epub 2019 Aug 13. Mol Cell Proteomics. 2019. PMID: 31409669 Free PMC article.