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The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats.
Getsy PM, Coffee GA, Bates JN, Parran T, Hoffer L, Baby SM, MacFarlane PM, Knauss ZT, Damron DS, Hsieh YH, Bubier JA, Mueller D, Lewis SJ. Getsy PM, et al. Among authors: lewis sj. Front Pharmacol. 2024 Aug 26;15:1444574. doi: 10.3389/fphar.2024.1444574. eCollection 2024. Front Pharmacol. 2024. PMID: 39253377 Free PMC article.
The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester.
Lewis THJ, May WJ, Young AP, Bates JN, Baby SM, Getsy PM, Ryan RM, Hsieh YH, Seckler JM, Lewis SJ. Lewis THJ, et al. Among authors: lewis sj. Biomed Pharmacother. 2022 Dec;156:113939. doi: 10.1016/j.biopha.2022.113939. Epub 2022 Oct 28. Biomed Pharmacother. 2022. PMID: 36411626 Free PMC article.
1,104 results