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Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas.
Gut. 2024 Sep 13:gutjnl-2024-332412. doi: 10.1136/gutjnl-2024-332412. Online ahead of print.
Gut. 2024.
PMID: 39277181
Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma.
Hosein AN, Dangol G, Okumura T, Roszik J, Rajapakshe K, Siemann M, Zaid M, Ghosh B, Monberg M, Guerrero PA, Singhi A, Haymaker CL, Clevers H, Abou-Elkacem L, Woermann SM, Maitra A.
Hosein AN, et al.
Gastroenterology. 2022 Apr;162(4):1303-1318.e18. doi: 10.1053/j.gastro.2021.12.273. Epub 2021 Dec 30.
Gastroenterology. 2022.
PMID: 34973294
Free PMC article.
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Acquired chemoresistance drives spatial heterogeneity, chemoprotection and collective migration in pancreatic tumor spheroids.
Thege FI, Cardle II, Gruber CN, Siemann MJ, Cong S, Wittmann K, Love J, Kirby BJ.
Thege FI, et al. Among authors: siemann mj.
PLoS One. 2022 May 26;17(5):e0267882. doi: 10.1371/journal.pone.0267882. eCollection 2022.
PLoS One. 2022.
PMID: 35617275
Free PMC article.
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