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Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors.
Velcicky J, Bauer MR, Schlapbach A, Lapointe G, Meyer A, Vögtle M, Blum E, Ngo E, Rolando C, Nimsgern P, Teixeira-Fouchard S, Lehmann H, Furet P, Berst F, Schümann J, Stringer R, Larger P, Schmid C, Prendergast CT, Riek S, Schmutz P, Lehmann S, Berghausen J, Scheufler C, Rondeau JM, Burkhart C, Knoepfel T, Gommermann N. Velcicky J, et al. Among authors: blum e. J Med Chem. 2024 Sep 26;67(18):16692-16711. doi: 10.1021/acs.jmedchem.4c01520. Epub 2024 Sep 14. J Med Chem. 2024. PMID: 39276085
Modulating ADME Properties by Fluorination: MK2 Inhibitors with Improved Oral Exposure.
Velcicky J, Schlapbach A, Heng R, Revesz L, Pflieger D, Blum E, Hawtin S, Huppertz C, Feifel R, Hersperger R. Velcicky J, et al. Among authors: blum e. ACS Med Chem Lett. 2018 Mar 20;9(4):392-396. doi: 10.1021/acsmedchemlett.8b00098. eCollection 2018 Apr 12. ACS Med Chem Lett. 2018. PMID: 29670707 Free PMC article.
Early-stage implementation of peer-led interventions for emergency department patients with substance use disorder: Findings from a formative qualitative evaluation.
Ibragimov U, Giordano NA, Amaresh S, Getz T, Matuszewski T, Steck AR, Schmidt M, Iglesias J, Li Y, Blum EH, Glasheen DA, Tuttle J, Pipalia H, Cooper HLF, Carpenter JE. Ibragimov U, et al. Among authors: blum eh. J Subst Use Addict Treat. 2024 Dec;167:209518. doi: 10.1016/j.josat.2024.209518. Epub 2024 Sep 13. J Subst Use Addict Treat. 2024. PMID: 39265917 Free article.
Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads.
Columbus I, Ghindes-Azaria L, Herzog IM, Blum E, Parvari G, Eichen Y, Cohen Y, Gershonov E, Drug E, Saphier S, Elias S, Smolkin B, Zafrani Y. Columbus I, et al. Among authors: blum e. Commun Chem. 2023 Sep 15;6(1):197. doi: 10.1038/s42004-023-01004-2. Commun Chem. 2023. PMID: 37715018 Free PMC article.
250 results