Horton BL - Search Results

1

Expansion of tumor-reactive CD8⁺ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade.

Morgan DM, Horton BL, Bhandarkar V, Van R, Dinter T, Zagorulya M, Love JC, Spranger S. Morgan DM, et al. Among authors: horton bl. Sci Immunol. 2024 Sep 13;9(99):eadi3487. doi: 10.1126/sciimmunol.adi3487. Epub 2024 Sep 13. Sci Immunol. 2024. PMID: 39270006 Free PMC article.

2

Lack of CD8⁺ T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer.

Horton BL, Morgan DM, Momin N, Zagorulya M, Torres-Mejia E, Bhandarkar V, Wittrup KD, Love JC, Spranger S. Horton BL, et al. Sci Immunol. 2021 Oct 29;6(64):eabi8800. doi: 10.1126/sciimmunol.abi8800. Epub 2021 Oct 29. Sci Immunol. 2021. PMID: 34714687 Free PMC article.

3

A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion.

Horton B, Spranger S. Horton B, et al. Immunity. 2018 Jul 17;49(1):11-13. doi: 10.1016/j.immuni.2018.07.001. Immunity. 2018. PMID: 30021140 Free PMC article.

4

Tissue Site and the Cancer Immunity Cycle.

Horton BL, Fessenden TB, Spranger S. Horton BL, et al. Trends Cancer. 2019 Oct;5(10):593-603. doi: 10.1016/j.trecan.2019.07.006. Epub 2019 Aug 13. Trends Cancer. 2019. PMID: 31706507 Free PMC article. Review.

5

CD36 - the Achilles' heel of T_reg cells.

Horton BL, Spranger S. Horton BL, et al. Nat Immunol. 2020 Mar;21(3):251-253. doi: 10.1038/s41590-020-0601-0. Nat Immunol. 2020. PMID: 32066948 No abstract available.

6

The non-T-cell-inflamed tumor microenvironment: contributing factors and therapeutic solutions.

Horton BL, Spranger S. Horton BL, et al. Emerg Top Life Sci. 2017 Dec 12;1(5):447-456. doi: 10.1042/ETLS20170073. Emerg Top Life Sci. 2017. PMID: 33525802

7

Something old, something new: The marriage of PD-1 and IL-2.

Horton BL, Spranger S. Horton BL, et al. Immunity. 2023 Jan 10;56(1):8-10. doi: 10.1016/j.immuni.2022.12.012. Immunity. 2023. PMID: 36630920 Free article.

8

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer.

Zagorulya M, Yim L, Morgan DM, Edwards A, Torres-Mejia E, Momin N, McCreery CV, Zamora IL, Horton BL, Fox JG, Wittrup KD, Love JC, Spranger S. Zagorulya M, et al. Among authors: horton bl. Immunity. 2023 Feb 14;56(2):386-405.e10. doi: 10.1016/j.immuni.2023.01.010. Epub 2023 Feb 2. Immunity. 2023. PMID: 36736322 Free PMC article.

9

Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2.

Horton BL, D'Souza AD, Zagorulya M, McCreery CV, Abhiraman GC, Picton L, Sheen A, Agarwal Y, Momin N, Wittrup KD, White FM, Garcia KC, Spranger S. Horton BL, et al. JCI Insight. 2023 Oct 9;8(19):e172728. doi: 10.1172/jci.insight.172728. JCI Insight. 2023. PMID: 37669107 Free PMC article.

10

Intratumoral CD8⁺ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.

Horton BL, Williams JB, Cabanov A, Spranger S, Gajewski TF. Horton BL, et al. Cancer Immunol Res. 2018 Jan;6(1):14-24. doi: 10.1158/2326-6066.CIR-17-0249. Epub 2017 Nov 2. Cancer Immunol Res. 2018. PMID: 29097422 Free PMC article.

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