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Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer.
Lee HM, Saw AK, Morris VK, Napolitano S, Bristow C, Srinivasan S, Peoples M, Sorokin A, Kanikarla Marie P, Schulz J, Singh AK, Terranova C, Coker O, Jain A, Kopetz S, Rai K. Lee HM, et al. Among authors: schulz j. Clin Cancer Res. 2024 Nov 15;30(22):5166-5179. doi: 10.1158/1078-0432.CCR-24-1166. Clin Cancer Res. 2024. PMID: 39269307
Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer.
Orouji E, Raman AT, Singh AK, Sorokin A, Arslan E, Ghosh AK, Schulz J, Terranova C, Jiang S, Tang M, Maitituoheti M, Callahan SC, Barrodia P, Tomczak K, Jiang Y, Jiang Z, Davis JS, Ghosh S, Lee HM, Reyes-Uribe L, Chang K, Liu Y, Chen H, Azhdarinia A, Morris J, Vilar E, Carmon KS, Kopetz SE, Rai K. Orouji E, et al. Among authors: schulz j. Gut. 2022 May;71(5):938-949. doi: 10.1136/gutjnl-2020-322835. Epub 2021 May 31. Gut. 2022. PMID: 34059508 Free PMC article.
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy.
Terranova CJ, Tang M, Maitituoheti M, Raman AT, Ghosh AK, Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL, Lazar AJ, Woodman SE, Bernatchez C, Rai K. Terranova CJ, et al. Among authors: schulz j. Cell Rep. 2021 Jul 20;36(3):109410. doi: 10.1016/j.celrep.2021.109410. Cell Rep. 2021. PMID: 34289358 Free PMC article.
Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state.
Kochat V, Raman AT, Landers SM, Tang M, Schulz J, Terranova C, Landry JP, Bhalla AD, Beird HC, Wu CC, Jiang Y, Mao X, Lazcano R, Gite S, Ingram DR, Yi M, Zhang J, Keung EZ, Scally CP, Roland CL, Hunt KK, Feig BW, Futreal PA, Hwu P, Wang WL, Lazar AJ, Slopis JM, Wilson-Robles H, Wiener DJ, McCutcheon IE, Wustefeld-Janssens B, Rai K, Torres KE. Kochat V, et al. Among authors: schulz j. Acta Neuropathol. 2021 Sep;142(3):565-590. doi: 10.1007/s00401-021-02341-z. Epub 2021 Jul 20. Acta Neuropathol. 2021. PMID: 34283254
High enhancer activity is an epigenetic feature of HPV negative atypical head and neck squamous cell carcinoma.
Callahan SC, Kochat V, Liu Z, Raman AT, Divenko M, Schulz J, Terranova CJ, Ghosh AK, Tang M, Johnson FM, Wang J, Skinner HD, Pickering CR, Myers JN, Rai K. Callahan SC, et al. Among authors: schulz j. Front Cell Dev Biol. 2022 Jul 19;10:936168. doi: 10.3389/fcell.2022.936168. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35927986 Free PMC article.
Claustrum volumes are lower in schizophrenia and mediate patients' attentional deficits.
Schinz D, Neubauer A, Hippen R, Schulz J, Li HB, Thalhammer M, Schmitz-Koep B, Menegaux A, Wendt J, Ayyildiz S, Brandl F, Priller J, Uder M, Zimmer C, Hedderich MD, Sorg C. Schinz D, et al. Among authors: schulz j. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Nov 26:S2451-9022(24)00350-1. doi: 10.1016/j.bpsc.2024.11.013. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 39608754
G2019S Mutation of Leucine-Rich Repeat Kinase 2 Is a Cause of Lewy Body Dementia in Patients With North African Ancestors.
Segers K, Benoit F, Levy S, Martinet V, Schulz JG, Bertrand F, De Bourgoing G, Tatillo C, Praet JP, Vandernoot I, Desmyter L, Peyrassol X, Kehagias P, Smits G, Dumoulin B, Besse-Hammer T, Dachy B, Surquin M. Segers K, et al. Among authors: schulz jg. Alzheimer Dis Assoc Disord. 2024 Oct-Dec 01;38(4):328-331. doi: 10.1097/WAD.0000000000000643. Epub 2024 Aug 7. Alzheimer Dis Assoc Disord. 2024. PMID: 39588689
1,873 results