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Page 1
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii.
Baker S, Krishna A, Higham S, Naydenova P, O'Leary S, Scott JB, Harcourt K, Forrest S, Goulding D, Thi Nguyen TN, Toan ND, Alekseeva E, Zhou Q, Andreozzi I, Sobotic B, Craig H, Wong V, Forrest-Owen N, Sanchez DM, Pearce C, Roberts L, Watson S, Clare S, Torok ME, Dougan G, Kellam P, Tregoning JS, Reece ST. Baker S, et al. Among authors: kellam p. Nat Commun. 2024 Sep 12;15(1):7979. doi: 10.1038/s41467-024-52357-8. Nat Commun. 2024. PMID: 39266557 Free PMC article.
IFITM3 restricts the morbidity and mortality associated with influenza.
Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, Chin CR, Feeley EM, Sims JS, Adams DJ, Wise HM, Kane L, Goulding D, Digard P, Anttila V, Baillie JK, Walsh TS, Hume DA, Palotie A, Xue Y, Colonna V, Tyler-Smith C, Dunning J, Gordon SB; GenISIS Investigators; MOSAIC Investigators; Smyth RL, Openshaw PJ, Dougan G, Brass AL, Kellam P. Everitt AR, et al. Among authors: kellam p. Nature. 2012 Mar 25;484(7395):519-23. doi: 10.1038/nature10921. Nature. 2012. PMID: 22446628 Free PMC article.
Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane.
Smith SE, Busse DC, Binter S, Weston S, Diaz Soria C, Laksono BM, Clare S, Van Nieuwkoop S, Van den Hoogen BG, Clement M, Marsden M, Humphreys IR, Marsh M, de Swart RL, Wash RS, Tregoning JS, Kellam P. Smith SE, et al. Among authors: kellam p. J Virol. 2019 Mar 5;93(6):e02003-18. doi: 10.1128/JVI.02003-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567988 Free PMC article.
Analysis of the B cell receptor repertoire in six immune-mediated diseases.
Bashford-Rogers RJM, Bergamaschi L, McKinney EF, Pombal DC, Mescia F, Lee JC, Thomas DC, Flint SM, Kellam P, Jayne DRW, Lyons PA, Smith KGC. Bashford-Rogers RJM, et al. Among authors: kellam p. Nature. 2019 Oct;574(7776):122-126. doi: 10.1038/s41586-019-1595-3. Epub 2019 Sep 25. Nature. 2019. PMID: 31554970 Free PMC article.
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.
Sallah N, Miley W, Labo N, Carstensen T, Fatumo S, Gurdasani D, Pollard MO, Dilthey AT, Mentzer AJ, Marshall V, Cornejo Castro EM, Pomilla C, Young EH, Asiki G, Hibberd ML, Sandhu M, Kellam P, Newton R, Whitby D, Barroso I. Sallah N, et al. Among authors: kellam p. Nat Commun. 2020 Jul 31;11(1):3849. doi: 10.1038/s41467-020-17696-2. Nat Commun. 2020. PMID: 32737300 Free PMC article.
Genome-wide evolutionary dynamics of influenza B viruses on a global scale.
Langat P, Raghwani J, Dudas G, Bowden TA, Edwards S, Gall A, Bedford T, Rambaut A, Daniels RS, Russell CA, Pybus OG, McCauley J, Kellam P, Watson SJ. Langat P, et al. Among authors: kellam p. PLoS Pathog. 2017 Dec 28;13(12):e1006749. doi: 10.1371/journal.ppat.1006749. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29284042 Free PMC article.
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter Š, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, Kellam P, Zavala F, Ward AB, Wilson IA. Oyen D, et al. Among authors: kellam p. PLoS Pathog. 2020 Mar 9;16(3):e1008373. doi: 10.1371/journal.ppat.1008373. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32150583 Free PMC article.
Patient-specific simulation as a basis for clinical decision-making.
Sadiq SK, Mazzeo MD, Zasada SJ, Manos S, Stoica I, Gale CV, Watson SJ, Kellam P, Brew S, Coveney PV. Sadiq SK, et al. Among authors: kellam p. Philos Trans A Math Phys Eng Sci. 2008 Sep 13;366(1878):3199-219. doi: 10.1098/rsta.2008.0100. Philos Trans A Math Phys Eng Sci. 2008. PMID: 18573758
318 results