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759 results

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Page 1
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii.
Baker S, Krishna A, Higham S, Naydenova P, O'Leary S, Scott JB, Harcourt K, Forrest S, Goulding D, Thi Nguyen TN, Toan ND, Alekseeva E, Zhou Q, Andreozzi I, Sobotic B, Craig H, Wong V, Forrest-Owen N, Sanchez DM, Pearce C, Roberts L, Watson S, Clare S, Torok ME, Dougan G, Kellam P, Tregoning JS, Reece ST. Baker S, et al. Among authors: dougan g. Nat Commun. 2024 Sep 12;15(1):7979. doi: 10.1038/s41467-024-52357-8. Nat Commun. 2024. PMID: 39266557 Free PMC article.
A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia.
Cuypers WL, Meysman P, Weill FX, Hendriksen RS, Beyene G, Wain J, Nair S, Chattaway MA, Perez-Sepulveda BM, Ceyssens PJ, de Block T, Lee WWY, Pardos de la Gandara M, Kornschober C, Moran-Gilad J, Veldman KT, Cormican M, Torpdahl M, Fields PI, Černý T, Hardy L, Tack B, Mellor KC, Thomson N, Dougan G, Deborggraeve S, Jacobs J, Laukens K, Van Puyvelde S. Cuypers WL, et al. Among authors: dougan g. Nat Commun. 2023 Jun 14;14(1):3517. doi: 10.1038/s41467-023-38902-x. Nat Commun. 2023. PMID: 37316492 Free PMC article. Review.
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE 3rd, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS, Darvish-Damavandi M, Mulcahy VL, Kuc RE, Williams TL, Heslop JA, Rossetti D, Tysoe OC, Galanakis V, Vila-Gonzalez M, Crozier TWM, Bargehr J, Sinha S, Upponi SS, Fear C, Swift L, Saeb-Parsy K, Davies SE, Wester A, Hagström H, Melum E, Clements D, Humphreys P, Herriott J, Kijak E, Cox H, Bramwell C, Valentijn A, Illingworth CJR; UK-PBC Consortium; Dahman B, Bastaich DR, Ferreira RD, Marjot T, Barnes E, Moon AM, Barritt AS 4th, Gupta RK, Baker S, Davenport AP, Corbett G, Gorgoulis VG, Buczacki SJA, Lee JH, Matheson NJ, Trauner M, Fisher AJ, Gibbs P, Butler AJ, Watson CJE, Mells GF, Dougan G, Owen A, Lohse AW, Vallier L, Sampaziotis F. Brevini T, et al. Among authors: dougan g. Nature. 2023 Mar;615(7950):134-142. doi: 10.1038/s41586-022-05594-0. Epub 2022 Dec 5. Nature. 2023. PMID: 36470304 Free PMC article.
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa.
Van Puyvelde S, de Block T, Sridhar S, Bawn M, Kingsley RA, Ingelbeen B, Beale MA, Barbé B, Jeon HJ, Mbuyi-Kalonji L, Phoba MF, Falay D, Martiny D, Vandenberg O, Affolabi D, Rutanga JP, Ceyssens PJ, Mattheus W, Cuypers WL, van der Sande MAB, Park SE, Kariuki S, Otieno K, Lusingu JPA, Mbwana JR, Adjei S, Sarfo A, Agyei SO, Asante KP, Otieno W, Otieno L, Tahita MC, Lompo P, Hoffman IF, Mvalo T, Msefula C, Hassan-Hanga F, Obaro S, Mackenzie G, Deborggraeve S, Feasey N, Marks F, MacLennan CA, Thomson NR, Jacobs J, Dougan G, Kariuki S, Lunguya O. Van Puyvelde S, et al. Among authors: dougan g. Nat Commun. 2023 Oct 23;14(1):6392. doi: 10.1038/s41467-023-41152-6. Nat Commun. 2023. PMID: 37872141 Free PMC article. Review.
A metagenomic prospective cohort study on gut microbiome composition and clinical infection in small bowel transplantation.
Madhav A, Bousfield R, Pereira-Dias J, Cormie C, Forrest S, Keane J, Kermack L, Higginson E, Dougan G, Spiers H, Massey D, Sharkey L, Rutter C, Woodward J, Russell N, Amin I, Butler A, Atkinson K, Dymond T, Bartholdson Scott J, Baker S, Gkrania-Klotsas E. Madhav A, et al. Among authors: dougan g. Gut Microbes. 2024 Jan-Dec;16(1):2323232. doi: 10.1080/19490976.2024.2323232. Epub 2024 Mar 4. Gut Microbes. 2024. PMID: 38439546 Free PMC article.
Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia.
Navapurkar V, Bartholdson Scott J, Maes M, Hellyer TP, Higginson E, Forrest S, Pereira-Dias J, Parmar S, Heasman-Hunt E, Polgarova P, Brown J, Titti L, Smith WP, Scott J, Rostron A, Routledge M, Sapsford D, Török ME, McMullan R, Enoch DA, Wong V; VAP-Rapid investigators; Curran MD, Brown NM, Simpson AJ, Herre J, Dougan G, Conway Morris A. Navapurkar V, et al. Among authors: dougan g. Wellcome Open Res. 2022 Oct 12;6:256. doi: 10.12688/wellcomeopenres.17099.3. eCollection 2021. Wellcome Open Res. 2022. PMID: 36337362 Free PMC article.
EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC. Randzavola LO, et al. Among authors: dougan gj. Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387. Elife. 2022. PMID: 36421765 Free PMC article.
759 results