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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival.
Lascaux P, Hoslett G, Tribble S, Trugenberger C, Antičević I, Otten C, Torrecilla I, Koukouravas S, Zhao Y, Yang H, Aljarbou F, Ruggiano A, Song W, Peron C, Deangeli G, Domingo E, Bancroft J, Carrique L, Johnson E, Vendrell I, Fischer R, Ng AWT, Ngeow J, D'Angiolella V, Raimundo N, Maughan T, Popović M, Milošević I, Ramadan K. Lascaux P, et al. Among authors: vendrell i. Cell. 2024 Sep 5:S0092-8674(24)00911-5. doi: 10.1016/j.cell.2024.08.020. Online ahead of print. Cell. 2024. PMID: 39265577 Free article.
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K. Vaz B, et al. Among authors: vendrell i. Mol Cell. 2016 Nov 17;64(4):704-719. doi: 10.1016/j.molcel.2016.09.032. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871366 Free PMC article.
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.
Fielden J, Wiseman K, Torrecilla I, Li S, Hume S, Chiang SC, Ruggiano A, Narayan Singh A, Freire R, Hassanieh S, Domingo E, Vendrell I, Fischer R, Kessler BM, Maughan TS, El-Khamisy SF, Ramadan K. Fielden J, et al. Among authors: vendrell i. Nat Commun. 2020 Mar 9;11(1):1274. doi: 10.1038/s41467-020-15000-w. Nat Commun. 2020. PMID: 32152270 Free PMC article.
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.
Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. Halder S, et al. Among authors: vendrell i. Nat Commun. 2019 Jul 17;10(1):3142. doi: 10.1038/s41467-019-11095-y. Nat Commun. 2019. PMID: 31316063 Free PMC article.
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.
Blest HTW, Redmond A, Avissar J, Barker J, Bridgeman A, Fowler G, Chauveau L, Hertzog J, Vendrell I, Fischer R, Iversen MB, Jing L, Koelle DM, Paludan SR, Kessler BM, Crump CM, Rehwinkel J. Blest HTW, et al. Among authors: vendrell i. Cell Rep. 2024 May 28;43(5):114122. doi: 10.1016/j.celrep.2024.114122. Epub 2024 Apr 22. Cell Rep. 2024. PMID: 38652659 Free article.
46 results