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The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats.
Getsy PM, Coffee GA, Bates JN, Parran T, Hoffer L, Baby SM, MacFarlane PM, Knauss ZT, Damron DS, Hsieh YH, Bubier JA, Mueller D, Lewis SJ. Getsy PM, et al. Among authors: coffee ga. Front Pharmacol. 2024 Aug 26;15:1444574. doi: 10.3389/fphar.2024.1444574. eCollection 2024. Front Pharmacol. 2024. PMID: 39253377 Free PMC article.
L-cysteine ethylester reverses the adverse effects of morphine on breathing and arterial blood-gas chemistry while minimally affecting antinociception in unanesthetized rats.
Baby SM, May WJ, Young AP, Wilson CG, Getsy PM, Coffee GA, Lewis THJ, Hsieh YH, Bates JN, Lewis SJ. Baby SM, et al. Among authors: coffee ga. Biomed Pharmacother. 2024 Feb;171:116081. doi: 10.1016/j.biopha.2023.116081. Epub 2024 Jan 13. Biomed Pharmacother. 2024. PMID: 38219385 Free PMC article.
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