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Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis.
Pinette JA, Myers JW, Park WY, Bryant HG, Eddie AM, Wilson GA, Montufar C, Shaikh Z, Vue Z, Nunn ER, Bessho R, Cottam MA, Haase VH, Hinton AO, Spinelli JB, Cartailler JP, Zaganjor E. Pinette JA, et al. Among authors: cartailler jp. J Lipid Res. 2024 Oct;65(10):100641. doi: 10.1016/j.jlr.2024.100641. Epub 2024 Sep 6. J Lipid Res. 2024. PMID: 39245323 Free article.
Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease.
Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schroeder KR, Valenti AM, Harrison FE, Hasty AH. Robertson KV, et al. Among authors: cartailler jp. Res Sq [Preprint]. 2024 Jun 27:rs.3.rs-4559940. doi: 10.21203/rs.3.rs-4559940/v1. Res Sq. 2024. Update in: J Neuroinflammation. 2024 Sep 27;21(1):238. doi: 10.1186/s12974-024-03238-w. PMID: 38978579 Free PMC article. Updated. Preprint.
Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease.
Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schleh MW, Schroeder KR, Valenti AM, Kramer AT, Harrison FE, Hasty AH. Robertson KV, et al. Among authors: cartailler jp. J Neuroinflammation. 2024 Sep 27;21(1):238. doi: 10.1186/s12974-024-03238-w. J Neuroinflammation. 2024. PMID: 39334471 Free PMC article.
Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice.
Dos Santos C, Cambraia A, Shrestha S, Cutler M, Cottam M, Perkins G, Lev-Ram V, Roy B, Acree C, Kim KY, Deerinck T, Dean D, Cartailler JP, MacDonald PE, Hetzer M, Ellisman M, Arrojo E Drigo R. Dos Santos C, et al. Among authors: cartailler jp. Nat Commun. 2024 Oct 21;15(1):9063. doi: 10.1038/s41467-024-53127-2. Nat Commun. 2024. PMID: 39433757 Free PMC article.
The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler JP, Sampson L, Magnuson MA, Jacobson DA. Nakhe AY, et al. Among authors: cartailler jp. Elife. 2024 May 3;12:RP89967. doi: 10.7554/eLife.89967. Elife. 2024. PMID: 38700926 Free PMC article.
42 results