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Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation.
Castillero E, Fitzpatrick E, Keeney SJ, D'Angelo AM, Pressly BB, Simpson MT, Kurade M, Erwin WC, Moreno V, Camillo C, Shukla HJ, Inamdar VV, Aghali A, Grau JB, Salvati E, Nissim I, Rauova L, Oyama MA, Stachelek SJ, Brown C, Krieger AM, Levy RJ, Ferrari G. Castillero E, et al. Among authors: grau jb. Sci Transl Med. 2023 Jan 4;15(677):eadc9606. doi: 10.1126/scitranslmed.adc9606. Epub 2023 Jan 4. Sci Transl Med. 2023. PMID: 36599005 Free PMC article.
Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis.
Anselmo W, Branchetti E, Grau JB, Li G, Ayoub S, Lai EK, Rioux N, Tovmasyan A, Fortier JH, Sacks MS, Batinic-Haberle I, Hazen SL, Levy RJ, Ferrari G. Anselmo W, et al. Among authors: grau jb. J Am Heart Assoc. 2018 Oct 16;7(20):e007861. doi: 10.1161/JAHA.117.007861. J Am Heart Assoc. 2018. PMID: 30371255 Free PMC article.
Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.
Branchetti E, Sainger R, Poggio P, Grau JB, Patterson-Fortin J, Bavaria JE, Chorny M, Lai E, Gorman RC, Levy RJ, Ferrari G. Branchetti E, et al. Among authors: grau jb. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):e66-74. doi: 10.1161/ATVBAHA.112.300177. Epub 2012 Dec 13. Arterioscler Thromb Vasc Biol. 2013. PMID: 23241403 Free PMC article.
82 results