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596 results

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Utilising accessible and reproducible neurological assessments in clinical studies: Insights from use of the Neurological Impairment Scale in the multi-centre COVID-CNS study.
Alam AM, Webb GW, Collie C, Mariathasan S, Huang Y, Hilton O, Shil R, Dodd KC, Lilleker JB, Smith CJ, Easton A, Tamborska A, Thomas RH, Davies NWS, Jenkins TM, Zandi M, Benjamin L, Ellul MA, Solomon T, Pollak TA, Nicholson T, Breen G, van Wamelen DJ, Wood NW, Michael BD; (on Behalf of the COVID-CNS Group). Alam AM, et al. Among authors: breen g. Clin Med (Lond). 2024 Sep;24(5):100241. doi: 10.1016/j.clinme.2024.100241. Epub 2024 Sep 6. Clin Med (Lond). 2024. PMID: 39244036 Free PMC article.
Addressing ethnic disparities in neurological research in the United Kingdom: An example from the prospective multicentre COVID-19 Clinical Neuroscience Study.
van Wamelen DJ, Rota S, Hartmann M, Martin NH, Alam AM, Thomas RH, Dodd KC, Jenkins T, Smith CJ, Zandi MS, Easton A, Carr G, Benjamin LA, Lilleker JB, Saucer D, Coles AJ, Wood N, Ray Chaudhuri K, Breen G, Michael BD; COVID-CNS consortium. van Wamelen DJ, et al. Among authors: breen g. Clin Med (Lond). 2024 May;24(3):100209. doi: 10.1016/j.clinme.2024.100209. Epub 2024 Apr 19. Clin Med (Lond). 2024. PMID: 38642613 Free PMC article.
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain.
Dunai C, Hetherington C, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Tharmaratnam K, Needham EJ, Williams R, Huang Y, Wood GK, Collie C, Fower A, Fox H, Ellul MA, Held M, Egbe FN, Griffiths M, Solomon T, Breen G, Kipar A, Cavanagh J, Irani SR, Vincent A, Stewart JP, Taams LS, Menon DK, Michael BD. Dunai C, et al. Among authors: breen g. Front Immunol. 2024 Oct 14;15:1440324. doi: 10.3389/fimmu.2024.1440324. eCollection 2024. Front Immunol. 2024. PMID: 39474424 Free PMC article.
Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.
Saez-Atienzar S, Souza CDS, Chia R, Beal SN, Lorenzini I, Huang R, Levy J, Burciu C, Ding J, Gibbs JR, Jones A, Dewan R, Pensato V, Peverelli S, Corrado L, van Vugt JJFA, van Rheenen W, Tunca C, Bayraktar E, Xia M; International ALS Genomics Consortium; ITALSGEN Consortium; SLAGEN Consortium; Project MinE ALS Sequencing Consortium; Iacoangeli A, Shatunov A, Tiloca C, Ticozzi N, Verde F, Mazzini L, Kenna K, Al Khleifat A, Opie-Martin S, Raggi F, Filosto M, Piccinelli SC, Padovani A, Gagliardi S, Inghilleri M, Ferlini A, Vasta R, Calvo A, Moglia C, Canosa A, Manera U, Grassano M, Mandrioli J, Mora G, Lunetta C, Tanel R, Trojsi F, Cardinali P, Gallone S, Brunetti M, Galimberti D, Serpente M, Fenoglio C, Scarpini E, Comi GP, Corti S, Del Bo R, Ceroni M, Pinter GL, Taroni F, Bella ED, Bersano E, Curtis CJ, Lee SH, Chung R, Patel H, Morrison KE, Cooper-Knock J, Shaw PJ, Breen G, Dobson RJB, Dalgard CL; American Genome Center; Scholz SW, Al-Chalabi A, van den Berg LH, McLaughlin R, Hardiman O, Cereda C, Sorarù G, D'Alfonso S, Chandran S, Pal S, Ratti A, Gellera C, Johnson K, Doucet-O'Hare T, Pasternack N, Wang T, Nath A, Siciliano G, Silani V, Başak AN, Veldink JH, Camu W, Glass J… See abstract for full author list ➔ Saez-Atienzar S, et al. Among authors: breen g. Cell Genom. 2024 Nov 13;4(11):100679. doi: 10.1016/j.xgen.2024.100679. Epub 2024 Oct 21. Cell Genom. 2024. PMID: 39437787 Free article.
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium; St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, Müller-Myhsok B, Świątkowska B, Schulze TG, Nöthen MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Landén M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Working Grou… See abstract for full author list ➔ Blokland GAM, et al. Among authors: breen g. Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23. Biol Psychiatry. 2022. PMID: 34099189 Free PMC article.
A hybrid model for predicting response to risperidone after first episode of psychosis.
Costa GO, Ota VK, Luiz MR, Rosa JS, Xavier G, Mauer JH, Santoro ML, Carvalho CM, Cavalcante DA, Bugiga AVG, Bressan RA, Breen G, Gadelha A, Noto C, Mazzotti DR, Belangero SI. Costa GO, et al. Among authors: breen g. Braz J Psychiatry. 2024 Jul 29. doi: 10.47626/1516-4446-2024-3608. Online ahead of print. Braz J Psychiatry. 2024. PMID: 39074074 Free article.
Genetic basis of early onset and progression of type 2 diabetes in South Asians.
Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs BM, Samuel M, Gafton J, Zöllner J, Spreckley M; Genes & Health Research Team; Langenberg C, van Heel DA, Mathur R, Siddiqui MK, Finer S. Hodgson S, et al. Nat Med. 2024 Nov 26. doi: 10.1038/s41591-024-03317-8. Online ahead of print. Nat Med. 2024. PMID: 39592779
Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study.
Hamilton F, Schurz H, Yates TA, Gilchrist JJ, Möller M, Naranbhai V, Ghazal P, Timpson NJ; Genes & Health Research Team; International Tuberculosis Host Genetics Consortium; Parks T, Pollara G. Hamilton F, et al. Lancet Microbe. 2024 Nov 20:100922. doi: 10.1016/S2666-5247(24)00162-9. Online ahead of print. Lancet Microbe. 2024. PMID: 39579785 Free article.
596 results