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Page 1
Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites.
Andrews KT, Fisher GM, Firmin M, Liepa AJ, Wilson T, Gardiner J, Mohri Y, Debele E, Rai A, Davey AK, Masurier A, Delion A, Mouratidis AA, Hutt OE, Forsyth CM, Burrows JN, Ryan JH, Riches AG, Skinner-Adams TS. Andrews KT, et al. Among authors: liepa aj. Eur J Med Chem. 2024 Nov 15;278:116796. doi: 10.1016/j.ejmech.2024.116796. Epub 2024 Aug 28. Eur J Med Chem. 2024. PMID: 39241483 Free article.
Binding inhibitors of the bacterial sliding clamp by design.
Wijffels G, Johnson WM, Oakley AJ, Turner K, Epa VC, Briscoe SJ, Polley M, Liepa AJ, Hofmann A, Buchardt J, Christensen C, Prosselkov P, Dalrymple BP, Alewood PF, Jennings PA, Dixon NE, Winkler DA. Wijffels G, et al. Among authors: liepa aj. J Med Chem. 2011 Jul 14;54(13):4831-8. doi: 10.1021/jm2004333. Epub 2011 Jun 7. J Med Chem. 2011. PMID: 21604761
Synthesis, binding and bioactivity of gamma-methylene gamma-lactam ecdysone receptor ligands: advantages of QSAR models for flexible receptors.
Birru W, Fernley RT, Graham LD, Grusovin J, Hill RJ, Hofmann A, Howell L, James PJ, Jarvis KE, Johnson WM, Jones DA, Leitner C, Liepa AJ, Lovrecz GO, Lu L, Nearn RH, O'Driscoll BJ, Phan T, Pollard M, Turner KA, Winkler DA. Birru W, et al. Among authors: liepa aj. Bioorg Med Chem. 2010 Aug 1;18(15):5647-60. doi: 10.1016/j.bmc.2010.06.020. Epub 2010 Jun 15. Bioorg Med Chem. 2010. PMID: 20619664
Parasiticidal 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilides.
Ali A, Altamore TM, Bliese M, Fisara P, Liepa AJ, Meyer AG, Nguyen O, Sargent RM, Sawutz DG, Winkler DA, Winzenberg KN, Ziebell A. Ali A, et al. Among authors: liepa aj. Bioorg Med Chem Lett. 2008 Jan 1;18(1):252-5. doi: 10.1016/j.bmcl.2007.10.090. Epub 2007 Oct 30. Bioorg Med Chem Lett. 2008. PMID: 18006308
Novel nonphenol oxidative coupling.
Kupchan SM, Liepa AJ, Kameswaran V, Bryan RF. Kupchan SM, et al. Among authors: liepa aj. J Am Chem Soc. 1973 Oct 3;95(20):6861-3. doi: 10.1021/ja00801a071. J Am Chem Soc. 1973. PMID: 4746284 No abstract available.
New alkaloids and related artifacts from Cyclea peltata.
Kupchan SM, Liepa AJ, Baxter RL, Hintz HP. Kupchan SM, et al. Among authors: liepa aj. J Org Chem. 1973 May 18;38(10):1846-52. doi: 10.1021/jo00950a016. J Org Chem. 1973. PMID: 4698926 No abstract available.
Total synthesis of the tumor-inhibitory alkaloid thalicarpine.
Kupchan SM, Liepa AJ, Kameswaran V, Sempuku K. Kupchan SM, et al. Among authors: liepa aj. J Am Chem Soc. 1973 May 2;95(9):2995-3000. doi: 10.1021/ja00790a044. J Am Chem Soc. 1973. PMID: 4694718 No abstract available.
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