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Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.
Abdelghany SM, Schmid D, Deacon J, Jaworski J, Fay F, McLaughlin KM, Gormley JA, Burrows JF, Longley DB, Donnelly RF, Scott CJ. Abdelghany SM, et al. Among authors: mclaughlin km. Biomacromolecules. 2013 Feb 11;14(2):302-10. doi: 10.1021/bm301858a. Epub 2013 Jan 31. Biomacromolecules. 2013. PMID: 23327610 Free PMC article.
Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.
Schmid D, Jarvis GE, Fay F, Small DM, Greene MK, Majkut J, Spence S, McLaughlin KM, McCloskey KD, Johnston PG, Kissenpfennig A, Longley DB, Scott CJ. Schmid D, et al. Among authors: mclaughlin km. Cell Death Dis. 2014 Oct 9;5(10):e1454. doi: 10.1038/cddis.2014.413. Cell Death Dis. 2014. PMID: 25299779 Free PMC article.
Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia.
McLornan D, Hay J, McLaughlin K, Holohan C, Burnett AK, Hills RK, Johnston PG, Mills KI, McMullin MF, Longley DB, Gilkes A. McLornan D, et al. Br J Haematol. 2013 Jan;160(2):188-98. doi: 10.1111/bjh.12108. Epub 2012 Nov 20. Br J Haematol. 2013. PMID: 23167276 Free article.
c-FLIP: a key regulator of colorectal cancer cell death.
Wilson TR, McLaughlin KM, McEwan M, Sakai H, Rogers KM, Redmond KM, Johnston PG, Longley DB. Wilson TR, et al. Among authors: mclaughlin km. Cancer Res. 2007 Jun 15;67(12):5754-62. doi: 10.1158/0008-5472.CAN-06-3585. Cancer Res. 2007. PMID: 17575142 Free article.
The pseudo-caspase FLIP(L) regulates cell fate following p53 activation.
Lees A, McIntyre AJ, Crawford NT, Falcone F, McCann C, Holohan C, Quinn GP, Roberts JZ, Sessler T, Gallagher PF, Gregg GMA, McAllister K, McLaughlin KM, Allen WL, Egan LJ, Ryan AE, Labonte-Wilson MJ, Dunne PD, Wappett M, Coyle VM, Johnston PG, Kerr EM, Longley DB, McDade SS. Lees A, et al. Among authors: mclaughlin km. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17808-17819. doi: 10.1073/pnas.2001520117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661168 Free PMC article.
26 results